Table 4.
Glycemic control and treatment of patients undergoing total pancreatectomy in long-term follow-up period categorized by preoperative glycemic status.
| Characteristics | Total | NDG | With pre-op DM | P value | |
|---|---|---|---|---|---|
| SDG | LDG | ||||
| N | 80 (100) | 34 (42.5) | 17 (21.3) | 29 (36.3) | – |
| Age at last follow-up (years) | 62.59 ± 10.41 | 60.53 ± 11.19c | 61.29 ± 12.10 | 65.76 ± 7.61a | 0.079 |
| BMI (kg/m2) | 20.33 ± 2.39 | 20.00 ± 2.31 | 20.03 ± 2.45 | 20.89 ± 2.44 | 0.290 |
| HbA1c (%) | 7.43 ± 0.76 | 7.32 ± 0.83 | 7.77 ± 0.88 | 7.36 ± 0.52 | 0.193 |
| Insulin regimen | 0.411 | ||||
| MDI | 63 (78.8) | 28 (82.4) | 12 (70.6) | 23 (79.3) | – |
| Premixed insulin | 3 (3.8) | 0 | 2 (11.8) | 1 (3.4) | – |
| Insulin pump | 14 (17.5) | 6 (17.6) | 3 (17.6) | 5 (17.2) | – |
| Daily insulin dose (units/kg/day) | 0.49 ± 0.19 | 0.42 ± 0.12c | 0.42 ± 0.17c | 0.60 ± 0.21ab | < 0.001 |
| Daily insulin dose (units/day) | 27.09 ± 11.88 | 23.00 ± 7.57c | 22.98 ± 9.41c | 34.28 ± 14.00ab | < 0.001 |
| Basal percentage (%) | 39.4 ± 16.4 | 37.2 ± 16.6 | 45.6 ± 17.4 | 38.4 ± 15.3 | 0.208 |
| Insulin pump | |||||
| N | 14 (100) | 9 (64.3)* | 5 (35.7) | – | |
| Daily insulin dose (units/kg/day) | 0.44 ± 0.14 | 0.38 ± 0.10 | 0.53 ± 0.15 | 0.043 | |
| Daily insulin dose (units/day) | 24.81 ± 8.05 | 22.02 ± 6.97 | 29.83 ± 8.02 | 0.081 | |
| Basal percentage (%) | 44.1 ± 14.5 | 43.4 ± 13.5 | 45.9 ± 17.2 | 0.743 | |
| Combined oral antidiabetic agent | 7 (8.8) | 1 (2.9) | 1 (5.9) | 5 (17.2) | 0.222 |
| Metformin | 3 (3.8) | 0 | 0 | 3 (10.3) | – |
| α-glucosidase inhibitors | 4 (5.0) | 1 (2.9) | 1 (5.9) | 2 (6.9) | – |
Data are presented as mean ± SD or number (percentage).
pre-op, preoperative; DM, diabetes mellitus; NDG, nondiabetic group; SDG, short-duration diabetic group; LDG, long-duration diabetic group; BMI, body mass index; HbA1c, glycosylated hemoglobin A1c; MDI, multiple daily insulin injections.
*Including seven preoperative nondiabetic patients and two short-duration diabetic patients.
aP < 0.05 vs NDG. bP < 0.05 vs SDG. cP < 0.05 vs LDG.
P values < 0.05 were shown in bold.