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. 2023 Feb 13;14:1087829. doi: 10.3389/fphys.2023.1087829

TABLE 3.

Sex-related cardiopulmonary differences.

VT1 VT2 VO2max
Variables Female Male Female Male Female Male
t% 44.67 ± 9.1 50.25 ± 16.08 68.22 ± 12.23 74.92 ± 13.42 --- --- ---- ---
Rf 36.09 ± 9.57 29.69 ± 7.09* 41.89 ± 8.72 36.33 ± 7.86 52.46 ± 9.86 51.18 ± 7.63
VT 1.367 ± 0.25 2.266 ± 0.5**** 1.572 ± 0.17 2.56 ± 0.52**** 1.86 ± 0.23 2.8 ± 0.52****
VE 47.07 ± 7.63 64.37 ± 10.57**** 64.76 ± 10.52 90 ± 16.08*** 96.47 ± 19.58 140.6 ± 23****
IV 1318 ± 226.6 2256 ± 454.2**** 1538 ± 164.7 2575 ± 486.2**** 1863 ± 249.2 2860 ± 517.6****
VO2 1687 ± 269 2624 ± 477**** 2106 ± 278.3 3251 ± 539.7**** 2599 ± 373.6 3863 ± 520.4****
VCO2 1468 ± 212.6 2421 ± 487.2**** 2052 ± 308.4 3322 ± 692.9**** 2885 ± 369.7 4406 ± 660.9****
RER 0.8721 ± 0.05 0.92 ± 0.056* 0.9752 ± 0.08 1.017 ± 0.07 1.12 ± 0.08 1.14 ± 0.07
VE/VO2 28.1 ± 3.58 24.74 ± 2.4** 31.06 ± 5.3 27.79 ± 2.89* 37.66 ± 9.14 36.41 ± 3.54
VE/VCO2 32.33 ± 4.66 27.02 ± 3.31*** 31.9 ± 5.03 27.42 ± 3.15** 33.65 ± 6.63 32.02 ± 3.46
METs 8.58 ± 1.39 10.91 ± 2.09** 10.72 ± 1.62 13.49 ± 2.31** 13.19 ± 1.68 16.01 ± 2.17**
HR 145.9 ± 13.1 146.4 ± 13.93 170 ± 9.46 169.7 ± 15.33 186.9 ± 5.47 189.5 ± 9.62
VO2/HR 11.58 ± 1.74 17.99 ± 3.17**** 12.44 ± 1.9 19.24 ± 3.07**** 13.94 ± 2.15 20.45 ± 2.92****
PetO2 97.73 ± 4.8 93.34 ± 4.2* 100.6 ± 4.94 96.95 ± 4.13* 105.2 ± 4.92 104.4 ± 3.17
PetCO2 37.86 ± 4.9 43.56 ± 4.61** 38.39 ± 5.21 43.39 ± 4.27** 37.21 ± 5.48 38.83 ± 3.65
FAT 5202 ± 2387 4953 ± 3235 2468 ± 2647 1576 ± 2456 114 ± 245.3 135.9 ± 630.3
CHO 6598 ± 1856 13617 ± 4628**** 12613 ± 3000 21944 ± 5149**** 19054 ± 2433 28536 ± 3759****
FAT% 43.63 ± 16.21 27.84 ± 18.28* 16.15 ± 16.94 7.265 ± 11.12 0.5 ± 1.03 0.3512 ± 1.6
CHO% 56.37 ± 16.21 72.16 ± 18.28* 83.85 ± 16.94 92.74 ± 11.12 99.5 ± 1.03 99.65 ± 1.6
Ti 0.8054 ± 0.17 1.015 ± 0.23* 0.6928 ± 0.11 0.85 ± 0.2* 0.57 ± 0.09 0.59 ± 0.1
Te 0.9854 ± 0.33 1.124 ± 0.26 0.8035 ± 0.2 0.9 ± 0.22 0.62 ± 0.14 0.63 ± 0.1
Ttot 1.791 ± 0.48 2.139 ± 0.47 1.496 ± 0.3 1.74 ± 0.41 1.19 ± 0.22 1.21 ± 0.19
Ti/Ttot 0.4565 ± 0.03 0.4747 ± 0.02 0.4675 ± 0.03 0.49 ± 0.03 0.48 ± 0.03 0.49 ± 0.02
VD/VT 0.1981 ± 0.02 0.1906 ± 0.02 0.2037 ± 0.03 0.2 ± 0.02 0.22 ± 0.03 0.24 ± 0.02
VT/Ti 1.713 ± 0.18 2.265 ± 0.38*** 2.31 ± 0.32 3.1 ± 0.57*** 3.35 ± 0.67 4.85 ± 0.82****
HRR 56.63 ± 14.08 53.65 ± 13.07 32.6 ± 9.94 30.35 ± 14.56 15.65 ± 6.26 10.57 ± 10.1
SV 92.36 ± 14.83 140.4 ± 24.18**** 87.3 ± 14.5 132.8 ± 22.3**** 85.81 ± 13.32 126.4 ± 18.53****
Power 155.56 ± 39.09 151.04 ± 46.90 250.00 ± 39.53 291.46 ± 34.12* 308.33 ± 35.36 342.08 ± 30.99**

Values are shown as mean ± standard deviation. t%: difference from VO2max in percentage; Rf: respiratory frequency; VT: tidal volume; VE: ventilation; IV: inspiratory volume; VO2: absolute oxygen consumption; VCO2: carbon dioxide production; RER: respiratory exchange ratio; VE/O2: ventilatory equivalent for oxygen; VE/CO2: ventilatory equivalent for carbon dioxide; VO2/kg: relative oxygen consumption; METs: metabolic equivalent of task; HR: heart rate; VO2/HR: oxygen pulse; PetO2: end tidal partial pressure of oxygen; PetCO2: end tidal partial pressure of carbon dioxide; FAT%: percentage of energy from fat; CHO%: percentage of energy from carbohydrate; Ti: inspiratory time; Te: expiratory time; Ttot: respiratory cycle duration; Ti/Ttot: inspiratory time divided by respiratory cycle duration; VD/VT: dead space; VT/Ti: ventilatory drive; HRR: heart rate reserve; SV: stroke volume. *p < 0.05; **p < 0.01; ***p < 0.001 and ****p < 0.0001.