Table 1.
Demographic and biochemical characteristics of the subjects used for the secondary analysis of the VITADOS cohort.
| Males (n = 12) | Females (n = 26) | |
|---|---|---|
| Age (years) | 13.3 (10.2–17.8) | 14.2 (10.5–17.8) |
| Tanner stage | ||
| Tanner 1 | 3 | 1 |
| Tanner 2 | 3 | 4 |
| Tanner 3 | 2 | 6 |
| Tanner 4 | 2 | 7 |
| Tanner 5 | 2 | 8 |
| Height (cm) | 161 (136–187) | 158 (143–180) |
| Height (SD) | 0.9 (−2.4–2.7) | 0.7 (−1.0–4.0) |
| Weight (kg) | 55 (26–77) | 47 (32–67) |
| Weight (SD) | 0.2 (−1.7–5.4) | 0.8 (−1.0–2.4) |
| BMI (percentile) | 25 (3–99) | 54 (20–97) |
| SBP (percentile) | 30 (5–88) | 29 (0–94) |
| DBP (percentile) | 34 (9–93) | 32 (2–92) |
| Creatinine (µmol/L) | 55 (43–94) | 54 (40–80) |
| eGFR (ml/min/1.73 m2) | 107 (71–129) | 107 (74–141) |
| Calcium (mmol/L) | 2.42 (2.24–2.57) | 2.37 (2.20–2.53) |
| Phosphate (mmol/L) | 1.40 (1.08–1.60) | 1.38 (0.93–1.61) |
| Phosphate SDS | −0.6 (−1.6–0.4) | −0.6 (−2.3–0.5) |
| PTH (ng/L) | 17 (10–24) | 17 (11–29) |
| ALP (UI/L) | 229 (84–524) | 176 (54–305) |
| 25OHD (nmol/L)* | 55 (30–66) | 65 (48–129) |
| 1,25(OH)2D3 (pmol/L) | 123 (98–173) | 142 (96–206) |
| FGF23 (UI/L) | 62 (43–98) | 74 (58–106) |
| ALP (UI/L) | 229 (84–524) | 176 (55–305) |
| BAP (UI/L) | 62 (17–194) | 57 (11–110) |
| CTX (µmol/L)* | 1,746 (1442–2410) | 1,414 (652–2260) |
| OCN (µg/L) | 71 (40–160) | 64 (27–238) |
| Total Ch (mmol/L) | 4.2 (3.3–5.1) | 4.3 (2.3–5.7) |
| LDL Ch (mmol/L) | 2.4 (1.7–3.2) | 2.5 (0.8–4.0) |
| HDL Ch (mmol/L) | 1.2 (0.8–2.1) | 1.5 (0.9–2.3) |
| TG (mmol/L) | 0.7 (0.3–1.9) | 0.6 (0.3–1.4) |
| ATX (ng/ml) | 1,109 (521–1455) | 977 (450–2201) |
Results are expressed as median (min–max).
cm, centimeters; kgs, kilograms; SD, standard deviation; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; SDS, standard deviation score; ALP, alkaline phosphatases; 25OHD, 25-hydroxy-vitamin D; 1,25(OH)2D3, 1,25-dihydroxy-vitamin D; FGF23, fibroblast growth factor 23; ALP, alkaline phosphatases; BAP, bone ALP; CTX, C-terminal fraction of type 1 collagen; OCN, osteocalcin; Ch, cholesterol; LDL Ch, low-density lipoprotein cholesterol; HDL Ch, high-density lipoprotein cholesterol; TG, triglycérides; ATX, autotaxin; eGFR, estimated glomerular filtration rate.
Comparison was made by using the Mann–Whitney test. *p < 0.05.