Table 2.
Heterogeneity and power analysis of asthma on epilepsy.
| Exposure\Outcome | Method | ILAEC (epilepsy) | FinnGen Consortium (epilepsy) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| MR-Egger intercept (P) | MR_PRESSO (P) | F-statistic | Cochran-Q (P) | MR-Egger intercept (P) | MR_PRESSO (P) | F-statistic | Cochran-Q (P) | ||
| Asthma | IVW | 0.01 (0.580) | 24.50 (0.300) | 44.35 | 22.45 (0.262) 22.06 (0.229) |
-0.02 (0.148) | 33.87 (0.580) | 326.03 | 29.86 (0.671) 27.67 (0.730) |
| MR-Egger | |||||||||
|
Asthma
(adult-onset) |
IVW | -0.09 (0.121) | 7.09 (0.534) | 20.64 | 5.08 (0.533) 1.61 (0.900) |
-0.02 (0.821) | 6.99 (0.914) | 119.51 | 5.92 (0.920) 5.87 (0.882) |
| MR-Egger | |||||||||
|
Asthma
(childhood-onset) |
IVW | -0.001 (0.957) | 45.19 (0.037) | 35.59 | 42.23 (0.031) 42.23 (0.023) |
0.02 (0.625) | 61.90 (0.065) | 330.98 | 58.87 (0.066) 58.54 (0.057) |
| MR-Egger | |||||||||
MR, Mendelian randomization; ILAEC, International League Against Epilepsy Consortium; IVW, inverse-variance weighted; MR_PRESSO, Mendelian Randomization Pleiotropy RESidual Sum and Outlier; P, P value.