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. 2023 Feb 13;14:1105949. doi: 10.3389/fmicb.2023.1105949

Table 3.

Expression levels filamentation and biofilm-related genes in biofilms of Candida albicans and Candida tropicalis incubated with LGG or LP8014 CFSs.

Condition Strain ALS1 ALS3 BCR1 EFG1 TEC1 UME6
NRQ* P NRQ P NRQ P NRQ P NRQ P NRQ P
LGG CFS SC5314 0.476 ± 0.054 0.0030 0.718 ± 0.184 0.2546 1.202 ± 0.174 0.3590 0.594 ± 0.087 0.0271 0.655 ± 0.124 0.0615 0.943 ± 0.146 0.6223
A14 0.573 ± 0.068 0.0104 0.675 ± 0.121 0.0697 0.996 ± 0.095 0.8976 0.729 ± 0.109 0.1076 0.694 ± 0.031 0.0012 1.213 ± 0.269 0.5191
A69 0.843 ± 0.102 0.1887 0.849 ± 0.126 0.2958 0.789 ± 0.064 0.0379 0.796 ± 0.138 0.2115 0.706 ± 0.049 0.0066 1.295 ± 0.296 0.3889
T18S 0.629 ± 0.150 0.0798 0.469 ± 0.110 0.0406 0.786 ± 0.307 0.4373 0.571 ± 0.156 0.1206 1.113 ± 0.432 0.8952 0.313 ± 0.146 0.0981
T38R 1.648 ± 0.119 0.0027 0.742 ± 0.069 0.0308 1.216 ± 0.119 0.1453 1.080 ± 0.066 0.2885 1.710 ± 0.096 0.0007 0.831 ± 0.129 0.2787
LP8014 CFS SC5314 0.583 ± 0.047 0.0029 0.314 ± 0.080 0.0082 0.783 ± 0.165 0.2598 0.562 ± 0.142 0.0584 0.791 ± 0.186 0.3267 0.434 ± 0.070 0.0064
A14 0.948 ± 0.155 0.6404 0.862 ± 0.084 0.1733 1.137 ± 0.029 0.0071 0.786 ± 0.019 0.0005 1.067 ± 0.108 0.6407 1.161 ± 0.170 0.4365
A69 1.176 ± 0.190 0.4526 0.593 ± 0.134 0.0629 0.812 ± 0.086 0.1070 0.764 ± 0.148 0.2222 0.887 ± 0.082 0.2243 1.048 ± 0.242 0.9855
T18S 0.664 ± 0.157 0.1052 0.440 ± 0.100 0.0299 0.819 ± 0.262 0.4574 0.736 ± 0.151 0.2000 1.279 ± 0.365 0.6558 0.360 ± 0.170 0.0956
T38R 1.770 ± 0.096 0.0004 0.700 ± 0.036 0.0021 0.954 ± 0.048 0.3908 0.930 ± 0.079 0.4156 1.342 ± 0.099 0.0186 0.609 ± 0.095 0.0373

*Expression levels are expressed as mean ± SEM of the normalized relative quantity (NRQ) obtained from triplicate experiments. NRQ of control group (MRS) is constantly 1.0 and not shown. p-value was obtained by comparing to the control group using Student’s t-test. Bold values denote statistical significance at p < 0.05.