Table 1.
Descriptive statistics for participants
| Full sample | Biomarker sample | |
|---|---|---|
| N | 193 | 148 |
| Age, Mean (SD) | 70.03 (8.59) | 69.22 (8.43) |
| Female sex, N (%) | 122 (63.21%) | 92 (62.16%) |
| White race, N (%) | 190 (98.45%) | 145 (97.97%) |
| Years of education, Mean (SD) | 17.32 (2.28) | 17.39 (2.23) |
| Global cognitive composite score, Mean (SD) | 0.46 (0.54) | 0.51 (0.52) |
| Episodic memory composite, Mean (SD) | 0.48 (0.46) | 0.53 (0.46) |
| Executive function composite, Mean (SD) | 0.14 (0.41) | 0.22 (0.42) |
| Baseline GDS total score, Mean (SD) | 0.99 (1.59) | 0.86 (1.52) |
| GDS ≥ 1, N (%) | 90 (46.63%) | 61 (41.22%) |
| GDS ≥ 2, N (%) | 42 (21.76%) | 28 (18.92%) |
| GDS ≥ 5, N (%) | 9 (4.66%) | 5 (3.38%) |
| Baseline NPI total score, Mean (SD) | 0.29 (0.72) | 0.29 (0.73) |
| Baseline NPI 0 versus 1+, N (%) | 35 (18.13%) | 27 (18.24%) |
| Number of visits over time, Mean (SD) | 3.82 (1.26) | 4.01 (1.20) |
| Years between baseline and last visit, Mean (SD) | 3.05 (1.24) | 3.17 (1.20) |
| PiB cortical DVR, Mean (SD) | – | 1.08 (0.15) |
| PiB Positive, N (%) | – | 44 (30.56%) |
| WMH volume cm3, Mean (SD) | – | 4399.83 (7099.06) |
| WMH volume in upper quartile, N (%) | – | 27 (18.24%) |
Biomarker sample, Individuals with WMH scan and 11C-PiB PET scan; N, number; SD, standard deviation; GDS, Geriatric Depression Scale-15; NPI, Neuropsychiatric Inventory; PiB, 11C-Pittsburgh Compound B; DVR, Distribution volume ratio; WMH, white matter hyperintensities.