Table 3.

Longitudinal mixed effects model results for baseline neuropsychiatric symptoms (NPS) in relation to the global cognitive composite score, episodic memory, and executive function (full sample; N = 193)

	Global cognition		Episodic memory		Executive function
	Estimate (SE)	p	Estimate (SE)	p	Estimate (SE)	p
GDS total
Time	−0.012 (0.024)	0.615	0.028 (0.025)	0.269	−0.093 (0.012)	0.001
GDS total	0.052 (0.040)	0.198	0.05 (0.042)	0.232	−0.042 (0.041)	0.31
GDS total × time	−0.007 (0.008)	0.404	−0.005 (0.008)	0.511	0.006 (0.007)	0.413
GDS ≥ 1
Time	−0.018 (0.027)	0.508	0.013 (0.028)	0.639	−0.114 (0.023)	<0.001
GDS ≥ 1	0.020 (0.129)	0.875	0.040 (0.134)	0.766	−0.267 (0.131)	0.043
GDS ≥ 1 × time	−0.004 (0.027)	0.888	0.014 (0.028)	0.609	0.048 (0.023)	0.041
NPI total
Time	−0.018 (0.023)	0.421	0.028 (0.024)	0.247	−0.087 (0.020)	<0.001
NPI total	−0.003 (0.089)	0.969	0.046 (0.093)	0.621	−0.267 (0.090)	0.003
NPI total × time	−0.005 (0.020)	0.804	−0.022 (0.021)	0.307	0.002 (0.018)	0.921
NPI ≥ 1
Time	−0.016 (0.023)	0.486	0.032 (0.024)	0.179	−0.087 (0.020)	<0.001
NPI ≥ 1	−0.039 (0.166)	0.817	0.043 (0.173)	0.806	−0.457 (0.168)	0.007
NPI ≥ 1 × time	−0.024 (0.035)	0.497	−0.066 (0.037)	0.078	0.007 (0.031)	0.835

All models adjusted for baseline age, gender, education, and their interactions with time.