Table 2.

The pro- and anti-tumoral effects of necroptosis in tumors.

	Necroptotic cell type	Tumor type
Anti-tumoral effects	TCs	Breast cancer [128]
		Cervical squamous cancer [29]
		Hepatocellular carcinoma [130]
		Colorectal cancer [144]
		Head and neck squamous cell carcinoma [127]
Pro-tumoral effects	TCs	PDA [147]
	ECs	Melanoma、Breast cancer
		Lung carcinoma [148]
	Intestinal epithelial cell	Colorectal cancer [144]
	Hepatocytes	ICC [114]

TCs tumoral Cells, ECs endothelial cells, PDA pancreatic ductal adenocarcinoma, ICC intrahepatic cholangiocarcinoma