Table 4. SAR Exploration of the Northern Parta.
IC50 and Ki values are geometric means of multiple independent measurements (n ≥ 3 for enzymatic and cellular hHSD17B13, n = 2 for enzymatic mHSD17B13). nd = not determined. *Real IC50 value unclear due to limits of the assay wall; Ki values (NAD+) should be used for comparison.