Table 1. Aspartate Analogues Inhibitors of EAAT2.

	IC50 (μM)			Ratio
Compounds	EAAT1	EAAT2	EAAT3	Ratio EAAT1 vs EAAT2	Ratio EAAT3 vs EAAT2	Ref
17	96 ± 13	31 ± 5.8	–	3.1	–	(163)
18	67 ± 7.5	5.5 ± 1	–	12.1	–	(163)
19	0.116	0.059	2.4	2.0	40.6	(170)
20	–	1.2	4.1	–	3.4	(170)
21	0.022	0.017	0.3	1.3	17.6	(170, 171)
22	–	0.021	0.034	–	1.6	(170)
23	2	0.1	10	20	100	(173)
24a	0.3	0.2	0.65	1.5	3.3	(173)
24b	0.15	0.1	0.2	1.5	2	(173)
24c	0.1	0.08	0.05	1.3	0.6	(173)
24d	3.8	0.1	2.4	38	24	(173)
25	2.9	0.13	14.5	22	111.5	(173)
26	5	0.08	3.8	62.5	47.5	(173)
27	0.8	2.4	1.2	0.3	0.5	(168)
28	18	28	13	0.6	0.5	(168)
29	1.6	4.7	2.0	0.3	0.4	(168)
30	100	2.8	150	35.7	53.5	(168)
31	2.3	0.5	20	4.6	40	(168)