Table 4.
VOC metabolite results (µg/g creatinine) for the training fire participants, stratified by participant type.
| Analyte | Firefighter Type | Collection Period | N (N of non-detects) | Mean | Median | Min-Max | P-value | General PopulationA (Non-Smoker/ Smoker) |
Biological Exposure indices (BEI)B | |
|---|---|---|---|---|---|---|---|---|---|---|
| Median | 95th Percentile | |||||||||
|
| ||||||||||
| 3HPMA | Firefighter Student | Pre | 36 (0) | 172 | 146 | 92.7 – 403 | 0.011 C | 175 / 508 | 835 / 2,579 | Not Available |
| 3 hr | 36 (0) | 342 | 211 | 96.3 – 1660 | ||||||
| Instructor | Pre | 12 (0) | 231 | 168 | 97.7 – 764 | 0.052 | ||||
| 3 hr | 12 (0) | 439 | 322 | 179 – 1230 | ||||||
| MUCA | Firefighter Student | Pre | 36 (7) | 74.0 | 34.0 | 8.03 – 499 | 0.015 D | Not Available | Not Available | 500 |
| 3 hr | 36 (11) | 42.8 | 28.6 | 14.9 – 222 | ||||||
| Instructor | Pre | 12 (3) | 28.7 | 27.4 | 13.6 – 49.9 | 0.038 C | ||||
| 3 hr | 12 (1) | 186 | 74.2 | 29.9 – 750 | ||||||
| PhMA | Firefighter Student | Pre | 36 (33) | 0.03 | 0.01 | 0.00 – 0.38 | 0.121 | Not Available | Not Available | 25 |
| 3 hr | 36 (31) | 0.05 | 0.01 | 0.00 – 0.44 | ||||||
| Instructor | Pre | 12 (11) | 0.02 | 0.01 | 0.00 – 0.16 | 0.016 C | ||||
| 3 hr | 12 (4) | 0.22 | 0.24 | 0.01 – 0.51 | ||||||
| MADA | Firefighter Student | Pre | 35 (0) | 141 | 134 | 48.7 – 259 | <0.001 C | 116 / 182 | 299 / 600 | 400,000 |
| 3 hr | 36 (0) | 244 | 227 | 124 – 549 | ||||||
| Instructor | Pre | 12 (0) | 114 | 97.2 | 51.2 – 178 | <0.001 C | ||||
| 3 hr | 12 (0) | 393 | 356 | 188 – 873 | ||||||
| BzMA | Firefighter Student | Pre | 36 (1) | 9.02 | 5.85 | 1.26 – 36.3 | 0.634 | 6.32 / 6.06 | 38.9 / 33.1 | Not Available |
| 3 hr | 36 (0) | 9.68 | 8.65 | 0.77 – 28.7 | ||||||
| Instructor | Pre | 12 (0) | 5.47 | 5.01 | 2.38 – 10.3 | 0.080 | ||||
| 3 hr | 12 (0) | 20.6 | 9.31 | 4.32 – 94.6 | ||||||
| 3MHA+ 4MHA |
Firefighter Student | Pre | 36 (0) | 100 | 77.4 | 54.0 – 293 | 0.002 C | 149 / 488 | 872 / 2,026 | 1,500,000 |
| 3 hr | 36 (0) | 133 | 104 | 69.1 – 298 | ||||||
| Instructor | Pre | 12 (0) | 117 | 89.5 | 60.7 – 377 | 0.619 | ||||
| 3 hr | 12 (0) | 131 | 121 | 59.4 – 271 | ||||||
| 2MHA | Firefighter Student | Pre | 36 (8) | 21.2 | 19.0 | 5.50 – 69.9 | 0.106 | 26.4 / 68.5 | 141 / 354 | 1,500,000 |
| 3 hr | 36 (8) | 26.7 | 18.9 | 9.33 – 92.7 | ||||||
| Instructor | Pre | 12 (0) | 23.8 | 15.8 | 4.43 – 101 | 0.227 | ||||
| 3 hr | 12 (0) | 33.7 | 31.9 | 14.7 – 63.5 | ||||||
| 4HBeMA | Firefighter Student | Pre | 36 (1) | 6.65 | 6.24 | 1.52 – 13.7 | 0.008 D | 4.02 / 15.5 | 14.9 / 87.9 | Not Available |
| 3 hr | 36 (2) | 5.25 | 4.40 | 1.61 – 13.5 | ||||||
| Instructor | Pre | 12 (0) | 5.22 | 5.16 | 2.68 – 7.74 | 0.292 | ||||
| 3 hr | 12 (0) | 4.62 | 4.66 | 1.81 – 7.35 | ||||||
National Health and Nutrition Examination Survey (NHANES) (2018). 2013–2014 data documentation, codebook, and frequencies. Volatile Organic Compounds & Metabolites - Urine (UVOC_H). Available at https://wwwn.cdc.gov/Nchs/Nhanes/2013-2014/UVOC_H.htm.
American Conference of Governmental Industrial Hygienists (ACGIH) (2021). “2021 TLVs and BEIs with 9th Edition Documentation”. Cincinnati, OH: ACGIH.
3-hr post-fire mean concentrations were significantly higher than pre-fire mean concentrations.
3-hr post-fire mean concentrations were significantly lower than pre-fire mean concentrations.