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. 2023 Jan 22;14(3):367–378. doi: 10.7150/jca.81027

Figure 4.

Figure 4

Erianin Inhibits Tumorigenicity of HuRCSCs in Nude Mice. (A) Morphology of the dorsal tumors of tumor-bearing mice in each group. (B) Effect of Erianin on tumor volume and weight in nude mice. *p < 0.05 vs. Saline; t test; n = 4. (C) H & E staining confirming renal clear cell carcinoma in each group. (D) Biochemical assay on LPO. *p < 0.05 vs. Saline; t test; n = 4. (E) The results of immunohistochemical staining showed that Erianin intervention could significantly upregulate the levels of METTL3, ALOX12 and others in tumor tissues, and downregulated the levels of Ki67 and GPX4.