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. 2023 Feb 27;21:68. doi: 10.1186/s12951-023-01820-7

Table 3.

List of nano-embolization system for imaging in TACE or TAE therapy of HCC

Imaging Embolism system Contrast agent Drugs Synergistic therapy Refs.
Ultrasonic imaging DOX-NPs-MB Microbubbles DOX Ultrasound and TACE therapy [78]
X-ray imaging(CT/DSA) Fe@EGaIn/CA Fe@EGaIn DOX PTT, PDT and TACE therapy [36]
BaSO4/ALG BaSO4 N/A TAE therapy [81]
Ta@CaAlg Tantalum NPs DOX TACE therapy [62]
MSMC MoS2 nanosheets N/A TAE and microwave ablation therapy [82]
MRI Fe@EGaIn/CA Fe@EGaIn NPs DOX PTT, PDT and TACE therapy [36]
SPION@PDA SPION DOX PTT and TACE therapy [54]
Fe3O4-MS Fe3O4 NPs ADM TACE, microwave ablation, and ferroptosis [60]

DOX-NPs-MB doxorubicin-loaded albumin nanoparticle-conjugated microbubble, Fe@EGaIn eutectic gallium-indium alloy nanodroplets containing iron nanoparticles, Fe@EGaIn/CA calcium alginate microspheres loaded with Fe@EGaIn NPs, BaSO4/ALG barium alginate microspheres loaded with in situ synthesized BaSO4 particles, Ta@CaAlg calcium alginate microspheres loaded with tantalum NPs, MSMC MoS2 nanosheets encapsulated in sodium alginate microcapsules, SPION@PDA polydopamine coated superparamagnetic iron oxide NPs, Fe3O4-MS homogenous gelatin microspheres co-loaded Fe3O4 NPs, ADM adriamycin