Table 3.

Relation for clinical and radiographic parameters with VAS pain and HAQ: multivariate linear regression

Dependent variable	Independent variable	β	95% CI	p-value	r-square
VAS pain
		Inclusion			0.24
	Female	−2.68	−9.46–4.10	0.44
	Age	−0.35	−0.56 to (−0.13)	<0.01
	TJC28	1.18	0.70–1.66	<0.001
	CRP	0.26	0.16–0.36	<0.001
	Symptom duration	−0.68	−1.78–0.42	0.22
		1 year after inclusion			0.24
	Female	−2.04	−8.37–4.29	0.53
	Age	−0.16	−0.36–0.03	0.10
	TJC28	1.97	1.34–2.60	<0.001
	ESR	0.28	0.13–0.42	<0.001
		2 years after inclusion			0.29
	Female	9.07	1.91–16.24	0.01
	Age	−0.26	−0.49 to (−0.03)	0.03
	TJC28	1.71	1.06–2.36	<0.001
	ESR	0.40	0.20–0.59	<0.001
	RF seropositivity	4.50	−2.62–11.62	0.21
	ES	−0.03	−0.53–0.48	0.92
		5 years after inclusion			0.24
	Female	3.41	−3.62–10.45	0.34
	Age	−0.01	−0.22–0.21	0.95
	TJC28	1.75	1.11–2.39	<0.001
	CRP	0.37	0.15–0.58	0.001
HAQ
		Inclusion			0.39
	Female	0.177	0.028–0.326	0.02
	Age	0.001	−0.004–0.006	0.63
	TJC28	0.039	0.028–0.050	<0.001
	CRP	0.007	0.005–0.009	<0.001
	ES	0.032	0.006–0.057	0.02
	Symptom duration	−0.020	−0.044–0.005	0.11
		2 years after inclusion			0.30
	Female	0.222	0.049–0.395	0.01
	Age	0.003	−0.002–0.009	0.22
	TJC28	0.040	0.024–0.055	<0.001
	ESR	0.010	0.006–0.015	<0.001
	ES	0.010	−0.002–0.022	0.09
		5 years after inclusion			0.28
	Female	0.292	0.091–0.492	<0.01
	Age	0.012	0.005–0.018	<0.001
	TJC28	0.037	0.018–0.055	<0.001
	ESR	0.003	−0.004–0.010	0.43
	ES	0.009	0.001–0.017	0.02

VAS visual analogue scale, CI confidence interval, RF rheumatoid factor, TJC28 tender joint count in 28 joints, CRP C-reactive protein, ESR erythrocyte sedimentation rate, ES erosion score, HAQ Health Assessment Questionnaire