Table 4.
Relation between clinical and radiographic parameters and VAS pain: generalized estimating equations
| Variable | Crude | Adj. for sex and age | Multivariate model |
|---|---|---|---|
| β (95% CI) | β (95% CI) | β (95% CI) | |
| Female sex | 2.96 (−2.01, 7.93) | − | 3.63 (−1.11, 8.37) |
| Age (per year) | −0.19 (−0.36, −0.01) | − | −0.26 (−0.43, −0.09) |
| Symptom duration (months) | −0.46 (−1.28, 0.37) | −0.56 (−1.39, 0.28) | − |
| RF seropositivity | 1.70 (−3.21, 6.61) | 1.44 (−3.49, 6.37) | − |
| Anti-CCP seropositivity | −1.28 (−4.06, 6.62) | 1.43 (−3.81, 6.67) | − |
| SJC28 | 1.90 (1.53, 2.27) | 1.92 (1.55, 2.30) | 1.59 (1.21, 1.96) |
| TJC28 | 1.79 (1.49, 2.10) | 1.78 (1.47, 2.08) | − |
| ESR (per mm/h) | 0.41 (0.32, 0.51) | 0.43 (0.34, 0.52) | 0.34 (0.24, 0.43) |
| CRP (per mg/l) | 0.36 (0.27, 0.44) | 0.37 (0.29, 0.45) | − |
| SHS | −0.04 (−0.18, 0.10) | −0.02 (−0.15, 0.12) | − |
| ES | −0.10 (−0.22, 0.43) | 0.12 (−0.19, 0.43) | − |
| JSNS | −0.12 (−0.30, 0.05) | −0.09 (−0.27, 0.09) | − |
Bold text indicates statistical significance with p-values <0.05. Italic text indicates p-values ≥0.05 and <0.10. Bold plus italic text indicates p-values <0.001. VAS visual analogue scale, CI confidence interval, RF rheumatoid factor, Anti-CCP anti-cyclic citrullinated peptide, SJC28 swollen joint count in 28 joints, TJC28 tender joint count in 28 joints, CRP C-reactive protein, ESR erythrocyte sedimentation rate, SHS Sharp-van der Heijde score, ES erosion score, JSNS joint space narrowing score