Table 5.
Relation between clinical and radiographic parameters and HAQ: univariate linear regression
| Variable | Inclusion | 2 years | 5 years |
|---|---|---|---|
| β (95% CI) | β (95% CI) | β (95% CI) | |
| Female sex | 0.164 (−0.013, 0.340) | 0.269 (0.079, 0.459) | 0.274 (0.062, 0.485) |
| Age (per year) | 0.004 (−0.002, 0.010) | 0.004 (−0.002, 0.010) | 0.012 (0.005, 0.018) |
| Symptom duration (months) | −0.053 (−0.080, −0.026) | −0.007 (−0.038, 0.023) | −0.008 (−0.042, 0.026) |
| Body mass index (per kg/m2) | 0.015 (−0.009, 0.038) | 0.014 (−0.011, 0.038) | - |
| RF seropositivity | −0.149 (−0.315, 0.017) | −0.101 (−0.281, 0.080) | −0.170 (−0.373, 0.032) |
| Anti-CCP seropositivity | −0.093 (−0.271, 0.084) | −0.144 (−0.341, 0.052) | −0.123 (−0.343, 0.097) |
| SJC28 | 0.042 (0.026, 0.057) | 0.039 (0.022, 0.056) | 0.044 (0.025, 0.063) |
| TJC28 | 0.043 (0.032, 0.055) | 0.050 (0.035, 0.065) | 0.052 (0.034, 0.070) |
| ESR (per mm/h) | 0.009 (0.006, 0.012) | 0.013 (0.009, 0.018) | 0.011 (0.004, 0.019) |
| CRP (per mg/l) | 0.009 (0.006, 0.011) | 0.010 (0.004, 0.016) | 0.005 (−0.001, 0.012) |
| SHS | 0.005 (−0.005, 0.015) | 0.005 (0, 0.011) | 0.007 (0.003, 0.011) |
| ES | 0.048 (0.018, 0.078) | 0.021 (0.008, 0.035) | 0.016 (0.008, 0.024) |
| JSNS | 0.001 (−0.012, 0.013) | 0.003 (−0.005, 0.011) | 0.010 (0.004, 0.016) |
Bold text indicates statistical significance with p-values <0.05. HAQ Health Assessment Questionnaire, CI confidence interval, RF rheumatoid factor, Anti-CCP anti-cyclic citrullinated peptide, SJC28 swollen joint count in 28 joints, TJC28 tender joint count in 28 joints, CRP C-reactive protein, ESR erythrocyte sedimentation rate, SHS Sharp-van der Heijde score, ES erosion score, JSNS joint space narrowing score