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. 2023 Feb 27;21:21. doi: 10.1186/s12958-023-01073-x

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© The Author(s) 2023

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — The KEGG metabolic network in which FF metabolites of DOR patients were involved. The metabolic network was based on KEGG global metabolic pathways. The red dots and red letters are the metabolites that were statistically significant between the GH and control groups. The yellow dots and black letters are identified metabolites that displayed no significance. The red lines are metabolic pathways that connect differential metabolites with the shortest distance. FF follicular fluid, DOR diminished ovarian reserve, GH growth hormone