Table 1.
Baseline Characteristics and Workflow Measures
| EVT alone group (n = 116) | Bridging therapy group (n = 118) | |
|---|---|---|
| Demographic characteristics | ||
| Age,median (IQR), y | 70 (60–77) | 70 (60–78) |
| Male sex no.% | 66 (56.9) | 66 (55.9) |
| Medical history | ||
| Hypertension | 69 (59.5) | 74 (62.7) |
| Atrial fibrillation | 62 (53.4) | 62 (52.5) |
| Smoking | 28 (24.1) | 29 (24.6) |
| Diabetes | 25 (21.6) | 20 (16.9) |
| Hyperlipidemia | 18 (15.5) | 22 (18.6) |
| Coronary heart disease | 30 (25.9) | 19 (16.1) |
| Clinical characteristics | ||
| Prestroke mRS score | ||
| 0 | 110 (94.8) | 107 (90.7) |
| 1 | 6 (5.2) | 11 (9.3) |
| Stroke etiology | ||
| Cardioembolism | 65 (56.0) | 69 (58.5) |
| Large artery atherosclerosis | 32 (27.6) | 28 (23.7) |
| Unknown | 15 (12.9) | 20 (16.9) |
| Other | 4 (3.4) | 1 (0.8) |
| Imaging characteristics | ||
| Baseline ASPECTS < 8 | 50 (43.1) | 52 (44.1) |
| Location of intracranial occlusion | ||
| Intracranial internal carotid artery | 18 (15.5) | 17 (14.4) |
| M1 middle cerebra lartery segment | 95 (81.9) | 99 (83.9) |
| M2 middle cerebral artery segment | 3 (2.6) | 2 (1.7) |
| Baseline NIHSS score ≥ 16 | 59 (50.9) | 65 (55.1) |
| Workflow times | ||
| Time from stroke onset to randomization | ||
| 0-3 h | 68 (58.6) | 68 (57.6) |
| 3-6 h | 48 (41.4) | 50 (42.4) |
| Arrival to intravenous alteplase, median (IQR), min | NA | 61 (49–81) |
| Arrival to arterial puncture, median (IQR), min | 101 (80–135) | 105 (80–132) |
| Onset to puncture, median (IQR), min | 200 (155–247) | 210 (179–255) |
Abbreviations: ASPECTS Alberta Stroke Program Early Computed Tomography Score, IQR Interquartile range, EVT Endovascular treatment, IVT Intravenous thrombolysis, NIHSS National Institutes of Health Stroke Scale, NA Not applicable