TABLE IV.

Results of Relevant Cardiovascular Diagnostic Investigations

No.	Study	ECG	Echocardiogram	Coronary angiogram	Cardiac enzymes	Diagnosis (KS type), as reported by the authors
1	Mori et al26 (1997)	Significant STEs in leads II, III, aVF, V5, and V6, with 2:1 AV block	Normal	Normal coronary trees; ergonovine provocation test showed severe spasm at middle portion of RCA and LCA accompanied by chest pain and ischemic ST changes promptly resolved by 2.5 mg intracoronary isosorbide dinitrate	NR	Vasospastic angina associated with anaphylactic reaction
2	Blanco et al17 (2003)	Elevation of the ST segment of leads V1–V4 indicative of anterior acute MI	Anterior hypokinesia with global EF of 49%	Normal, with no atherosclerotic organic lesions	Elevated total CK and troponin T	Anterior acute MI associated with anaphylactic reaction
3	Gluvic et al22 (2007)	Up to 5-mm STE in inferior and entire precordial leads	No motility disorders of heart muscle (EF, 53%; trace mitral and tricuspid regurgitation)	Not performed (refused by patient)	Elevated CK, normal troponin I	ACS associated with type I hypersensitivity reaction
4	de Groot et al20 (2009)	STEs in leads II, III, and aVF; acute inferolateral MI diagnosed	NR	No significant coronary stenosis	Elevated troponin T, whereas CK, and CK-MB remained normal	STEMI associated with anaphylaxis
5	Cakar et al19 (2011)	First time: 1-mm STE in inferior derivations, reciprocal ST-segment depression up to 4 mm in entire precordial leads and third-degree AV block Second time: same as previously	NR	First time: 2 sequential 70% RCA lesions and noncritical lesion in LAD	Normal	ACS associated with anaphylaxis (first time: II; second time: I and II)
6	Granitz et al34 (2011)	Transient STEs over inferior posterior wall	NR	Stenosing CAD could be ruled out angiographically, but ubiquitous plaques found	Elevated troponin, without CK deflection	ACS associated with anaphylactic reaction (II)
7	Cagliyan et al18 (2013)	Emergent ECG compatible with acute anterior MI; fourth-hour control ECG showed resolution of STE	NR	LAD occluded just distal to the first diagonal branch	Marked elevation	Anterior acute MI triggered by allergic reaction (II)
8	Rodrigues et al2 (2013)	STE in the inferior leads	No motility disorders of heart wall muscle or other abnormalities	No lesions on coronary vessels or contractility abnormalities	Elevated troponin I and CK-MB	ACS associated with anaphylaxis (I)
9	Tiwari et al32 (2013)	STE in leads II, III, and aVF; STEMI of inferior wall diagnosed	NR	Normal coronary vessels	Elevated troponin T, normal CK, and CK-MB	STEMI associated with anaphylaxis (I)