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. 2023 Feb 13;14:1115031. doi: 10.3389/fimmu.2023.1115031

Table 1.

Baseline characteristics of the 320 patients with ICH.

Total (n=320) SAP development ICU admission
SAP (n=126) Non-SAP(n=194) P value ICU (n=112) Non-ICU (n=208) P value
Demographics
 Age, years, median (IQR) 62.5 (51.3-73.0) 65.5 (52-78) 62 (50-71.25) 0.103 63.5 (51.0-74.0) 62.0 (52.0-72.0) 0.781
 Sex, male, n (%) 213 (66.6%) 87 (69%) 126 (64.9%) 0.448 79 (70.5%) 134 (64.4%) 0.269
Clinical features
 GCS, median (IQR) 13 (7-15) 9 (6-12) 15 (11-15) <0.001 9 (6-12) 15 (10-15) <0.001
 NIHSS,
 median (IQR)
11 (3-35) 19 (11-35) 5 (2-14) <0.001 20 (12.3-35) 5 (2-14.8) <0.001
 Hematoma volume, ml,
 mean±SD
25.7 ± 20.8 32.4 ± 28.5 20.0 ± 17.6 <0.001 36.4 ± 29.4 19.9 ± 26.8 <0.001
 NLR, median (IQR) 6.78
(3.68-12.27)
10.30
(6.46-15.60)
4.79
(2.82-8.95)
<0.001 10.2 (6.5-15.4) 4.97 (2.88-9.72) <0.001
 SII, median (IQR) 1349.50
(755.28-2665.64)
2271.18
(1140.25-3232.95)
1018.04
(608.02-2075.39)
<0.001 2271.18(1167.97-3275.65) 1033.87 (609.60-2254.91) <0.001
 PLR, median (IQR) 169.98
(122.03-246.61)
193.85
(133.87-288.69)
159.38
(115.96-211.16)
0.001 188.00
(131.45-289.16)
163.49 (119.42-217.14) 0.008
 SIRI, median (IQR) 3.93 (1.82-7.45) 5.82 (2.96-11.67) 2.82 (1.36-5.56) <0.001 6.68(2.92-11.13) 3.02 (1.53-6.00) <0.001
Medical history
 Smoking, n (%) 71 (22.2%) 29 (23.0%) 42 (21.6%) 0.774 28 (25.0%) 43 (20.7%) 0.374
 Drinking, n (%) 40 (12.5%) 14 (11.1%) 26 (13.4%) 0.545 13 (11.6%) 27 (13%) 0.723
 Hypertension, n (%) 228 (71.3%) 87 (69%) 141 (72.7%) 0.483 76 (67.9%) 152 (73.1%) 0.325
 Diabetes, n (%) 43 (13.4%) 15 (11.9%) 28 (14.4%) 0.517 16 (14.3%) 27 (13.0%) 0.744
 Hyperlipidemia, n (%) 24 (7.5%) 6 (4.8) 18 (9.3%) 0.134 5 (4.5%) 19 (9.1%) 0.130
 COPD, n (%) 11 (3.4%) 6 (4.8%) 5 (2.6%) 0.352 4 (3.6%) 7(3.4%) 0.923
Treatment
 Nasogastric tube, n (%) 183 (57.1%) 106(84.1%) 77(39.7%) <0.001 97 (86.6%) 86 (41.3%) <0.001
 Neurosurgery, n (%) 96 (30.0%) 62(49.2%) 34(17.5%) <0.001 60 (53.6%) 36 (11.3%) <0.001

ICH, intracerebral hemorrhage; IQR, interquartile range; RR, relative risk; CI, confidence interval; GCS, Glasgow Coma Scale; NIHSS, National Institute of Health Stroke Scale; NLR, neutrophil-to-lymphocyte ratio; SII, systemic immune-inflammation index; PLR, platelet-to-lymphocyte ratio; SIRI, systemic inflammation response index; COPD, chronic obstructive pulmonary disease. The P values < 0.05 are written in bold text.