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. 2023 Feb 13;14:1115031. doi: 10.3389/fimmu.2023.1115031

Table 2.

AUC in predicting SAP occurrence, ICU admission and good outcomes at discharge.

AUC (95% CI) Cutoff point Sensitivity Specificity PPV NPV
AUC in predicting SAP occurrence
NLR 0.748 (0.695-0.801) 6.06 0.794 0.608 0.568 0.819
SII 0.707 (0.650-0.763) 1039 0.825 0.521 0.528 0.821
PLR 0.612 (0.548-0.677) 187.5 0.540 0.675 0.519 0.693
SIRI 0.707 (0.650-0.764) 2.291 0.500 0.438 0.865 0.833
AUC in predicting ICU admission
NLR 0.732 (0.671-0.786) 5.50 0.866 0.534 0.495 0.874
SII 0.701 (0.644-0.758) 1039 0.839 0.505 0.475 0.854
PLR 0.590 (0.522-0.657) 222.9 0.420 0.769 0.495 0.714
SIRI 0.680 (0.620-0.734) 2.802 0.795 0.481 0.447 0.807
AUC in predicting good outcomes at discharge
NLR 0.761 (0.707-0.814) 7.19 0.811 0.612 0.523 0.858
SII 0.758 (0.705-0.812) 1384 0.802 0.632 0.532 0.792
PLR 0.642 (0.581-0.703) 185.1 0.784 0.536 0.473 0.834
SIRI 0.722 (0.665-0.779) 2.676 0.595 0.751 0.217 0.394

AUC, area under receiver operating characteristic; NLR, neutrophil-to-lymphocyte ratio; SII, systemic immune-inflammation index; PLR, platelet-to-lymphocyte ratio; SIRI, systemic inflammation response index; SAP, stroke-associated pneumonia; ICU, intensive care unit.