Table 4.
Logistic analysis of the association between the CSIT score and olfactory impairment severity with the risk of MCI and AD.
| MCI vs. NC | MCI vs. AD | AD vs. NC | ||||
|---|---|---|---|---|---|---|
| CSIT score | Olfactory impairment severity | CSIT score | Olfactory impairment severity | CSIT score | Olfactory impairment severity | |
| Model 1 * | ||||||
| OR [95%CI]; P | 0.59 [0.50, 0.69], P < 0.001 | 2.83 [1.92, 4.17], P < 0.001 | 0.76 [0.67, 0.87]; P < 0.001 | 1.84 [1.35, 2.52], P < 0.001 | 0.55 [0.44, 0.67]; P < 0.001 | 3.69 [2.31, 5.90], P < 0.001 |
| Model 2 * | ||||||
| OR [95%CI]; P | 0.62 [0.53, 0.73]; P < 0.001 | 2.35 [1.58, 3.50]; P < 0.001 | 0.81 [0.69, 0.95]; P = 0.008 | 1.55 [1.09, 2.21]; P = 0.015 | 0.59 [0.47, 0.74]; P < 0.001 | 2.81 [1.65, 4.77]; P < 0.001 |
| Model 3 * | ||||||
| OR [95%CI]; P | 0.61 [0.52, 0.72]; P < 0.001 | 2.38 [1.59, 3.57]; P < 0.001 | 0.80 [0.68, 0.93]; P = 0.005 | 1.61 [1.12, 2.30]; P = 0.010 | 0.58 [0.45, 0.73]; P < 0.001 | 2.88 [1.67, 4.97]; P < 0.001 |
Model 1: non-adjusted model.
Model 2: adjusted for age, gender, and education levels.
Model 3: further adjusted for hypertension, hyperlipidemia, diabetes, CAD, and sleep disorder based on Model 2.