TABLE 1.
The list of Golgi protein effected by acute COG4 depletion
| Effect of acute COG4 depletion on Golgi protein | |||
|---|---|---|---|
| Early COG4 sensitive proteins (30–60 min depletion of COG4) | CCD vesicle protein (2 h depletion of COG4) | COG4‐insensitive Golgi proteins | |
| COG subunits |
COG1, COG3, COG8 |
||
| SNAREs |
GS15/BET1L, GS28/GOSR1 |
GS15/BET1L, GS28/GOSR1 |
STX5, YKT6 |
| Coiled‐coil tethers |
Giantin/GOLGB1, TMF1/ARA160 |
Golgin84/GOLGA5, TMF1/ARA160 |
GM130/GOLGA2, P115/USO1 GOLGA1/Golgin97 GOLGA4/Golgin245 |
| Small GTPases | Rab1B |
Rab2A, Rab6A, Rab30A, Rab43A |
|
| Coat proteins |
β′COP/COPB2, γCOP/COPG1, GGA2, AP1β/AP1B1 |
||
| Golgi enzymes |
B4GalT1, MGAT1 |
B4GalT1, MGAT1, GalNAcT2, Fut8 |
|
| Other Golgi resident proteins |
TMEM165/TPARL, GPP130/GOLIM4, TGN46/TGOLN2, Cab45/SDF4 |
GPP130/GOLIM4, Cab45/SDF4 |
ERGIC53/LMAN1 |
| Cargo adaptor protein | GOLPH3 | ||