Skip to main content
. 2023 Feb 7;10:rbad005. doi: 10.1093/rb/rbad005

Table 1.

Overview of advanced biomaterials in plastic surgery

Clinical administration Biomaterial Material type Clinical usage Clinical degradation Properties
Injection HA
  • Natural biomaterial: bovine derived

  • Synthetic biomaterial: non-animal derived

Esthetic filler
  • Temporary

  • Pure HA: 3–6 months

  • HA conjugated to another polymer: 6–12 months

Promotes the generation of Type I and Type III Collagen
CaHA Synthetic biomaterial Esthetic filler
  • Semipermanent

  • 12–18 months

Stimulates collagen generation
PLLA [10] Synthetic biomaterial Esthetic filler
  • Semipermanent

  • Up to 2 years

Promotes the generation of Type I and Type III Collagen
Collagen [11] Natural biomaterial Esthetic filler
  • Temporary

  • 9–18 months depending on no. of injections

Replaces collagen environment lost with age
Implant ADM Semisynthetic biomaterial Support Silicone Breast Implants Permanent Scaffold for host cells to repopulate and revascularize
Bioceramics Synthetic biomaterial Bone defect reconstruction Permanent Promotes osteogenesis and osteoinductivity

HA, hyaluronic acid; PRP, platelet-rich plasma; PLLA, poly-l-lactic acid; CaHA, calcium hydroxyapatite; ADM, acellular dermla matrices.