Date	Event	Description
27 February 2023	New search has been performed	Based on an updated search, 20 new studies were included in the review (Akturk 2018; Boonhong 2017; Chesterton 2018; De Moraes 2021; Eraslan 2014; Gatheridge 2020; Geler Kulcu 2016; Hall 2013; Jaladat 2017; Kocaoglu 2017; Oncu 2014; Rioja Toro 2012; Sanaee 2017; Schmid 2012; So 2018; Ulucakoy 2020; Wang 2017; Willis 2016; Wu 2017; Yazdanpanah 2012); eight studies, included in the previous version of this review, remain included (De Entrambasaguas 2006; Madjdinasab 2008; Manente 2001; Mishra 2006; Premoselli 2006; Sevim 2004; Walker 2000; Werner 2005); one study, which was awaiting classification in the previous version of this review, is now included (Taspinar 2007).
27 February 2023	New citation required and conclusions have changed	Data, which were not pooled in meta‐analysis in the previous version of this review, are now combined (i.e. Manente 2001 and Premoselli 2006 at short‐term analysis). The previous version of this review did not include any data from Sevim 2004 in analysis, but we have included them.  We excluded the following comparisons (included in the previous version of this review): Different splint designs were excluded until splints show efficacy since all identified comparisons tested some specific splint against another specific splint and inference to other splints is limited; Splint versus interventions that are unlikely disease modifying or it was impossible isolate the effect of splint (splint versus yoga; splint verus acupuncture; splint plus nerve and tendon gliding exercises with gabapentin plus nerve and tendon gliding exercises; splint plus steroid injection versus therapeutic ultrasound; splint plus steroid injection plus nerve and tendon gliding exercises versus nerve and tendon gliding exercises; splint plus steroid injection versus nerve and tendon gliding exercises; splint plus NSAID versus local corticosteroid injection). Changes to outcomes: The primary outcome is amended from "short‐term overall improvement" (in the previous version of this review) to "CTS symptoms" because the included studies did not measure this outcome in the previous review and preliminary overview (before data extraction) suggested that this outcome is rarely measured and reported. We excluded "improvement in neurophysiologic parameters" from the outcomes since they are not patient‐important outcomes. We added "referral to surgery" as an outcome, because it may be important outcome in clinical decision making.