IRCT2014020416485N1.

Methods	Study design:  Randomised, not blinded, parallel‐group, placebo‐controlled Setting: Baqiyatallah University of Medical Sciences polyclinic and University of Social Welfare and Rehabilitation Sciences affiliated clinics
Participants	Details of sampling frame: Target sample size: 150 Gender: Both Age: No age limit Duration of CTS symptoms (N of participants): Inclusion criteria: People with mild to moderate CTS with no history of surgical and local steroid injection, any age or gender Exclusion criteria: Severe CTS and severe dysfunction that needs surgical median nerve release History of other therapeutic approaches History of allergy against steroids or triamcinolone Steroid contraindications History of cardiac arrhythmia Diabetes mellitus Hand surgeries in past 3 months Rheumatoid arthritis Cervical radiculopath Thyroid dysfunctions
Interventions	Group 1: injection of 80 mg triamcinolone with 1 mL lidocaine 2% by hydrodissection method Group 2: injection of 40 mg triamcinolone with 1 mL distilled water and 1 ml lidocaine 2% by hydrodissection method Group 3: injection of 2 mL distilled water and 1 mL lidocaine 2% by hydrodissection method Group 4: injection of 40 mg triamcinolone without hydrodissection method Group 5: wrist splinting for 6 weeks
Outcomes	BCTQ score Median nerve ultrasound study Median nerve conduction study Pain score
Notes	Recruitment complete