Skip to main content
. 2023 Feb 27;2023(2):CD010003. doi: 10.1002/14651858.CD010003.pub2

Soon 2015.

Methods Single‐blinded, randomised clinical trial with a 2 × 2 factorial design
Setting: university clinical research centre and a network of clinical practices
Participants Total n = 120 participants
Group 1 (splint + multimodal approach comprising of manual mobilisation techniques, education and nerve and tendon gliding exercises (MEX)) n = 30
Group 2 (splint + ultrasound) n = 30
Group 3 (MEX alone) n = 30
Group 4 (ultrasound alone) n = 30
Inclusion criteria: 
Mild‐to‐moderate CTS based on clinical criteria and electrodiagnostic tests
Interventions Group 1: splint + MEX
Group 2: splint + ultrasound 
Group 3: MEX alone 
Group 4: ultrasound alone
Commercially available hand splint was used to keep the wrist in the neutral position. Participants who received the hand splint were advised to use the splint during sleep.
Outcomes Outcomes evaluated at baseline and at 7, 12 and 52 weeks follow‐up
  1. BCTQ 

  2. 6‐point global rating of change scale (GROC, 1 = much worse, 2 =worse, 3 = no change, 4 = improved, 5 = much improved, 6 = completely recovered)

  3. Electrodiagnostic test 

  4. 36‐item Short Form Health Survey (SF‐36) 

  5. Grip and tip‐pinch strength using a digital dynamometer

Notes Report available only as a conference abstract

BCTQ: Boston Carpal Tunnel Questionnaire
CTS: carpal tunnel syndrome
DML: distal motor latency
EMG: electromyography
GROC: Global Rating of Change
MEX: multimodal approach comprising of manual mobilisation techniques, education and nerve and tendon gliding exercises
NCV: nerve conduction velocity
RCT: randomised controlled trial
SF‐36: 36‐Item Short Form Health Survey
SNCV: sensory nerve conduction velocity
VAS: visual analog scale