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. 2023 Feb 13;14:1090906. doi: 10.3389/fendo.2023.1090906

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Copyright © 2023 Dong, Yuan, Ren, Li, Guo, Guan, Jiang, Qi and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparative immunological status examination of two molecular groups. (A-D) Comparative analysis of the TME components. (E) The plot illustrates the link between the score for oxidative metabolism and the infiltration of immune cells. (F-K) The scatter figure illustrates the link between the oxidative metabolism score and six substances associated with immune infiltration. A favorable correlation was identified between the oxidative metabolism score and the infiltration of macrophages, CCR, mast cells, type II IFN response, DCs, and T helper cells. (L) Comparison of the three subtypes’ immune checkpoint gene expression using a differential analysis method. *P < 0.05; **P < 0.01; ***P < 0.001.