TABLE 3. Serum IL‐31 levels in patients with noncirrhotic NASH with pruritus treated with cilofexor 100 mg.

	Max Grade 0–1 pruritus (n = 48)		Max Grade 2–3 pruritus (n = 8)
Visit	n a	Median (IQR)	n a	Median (IQR)	Wilcoxon p value
Baseline	46	0.078 (0.062, 0.19)	8	0.11 (0.062, 0.23)	0.662
Week 1	46	0.18 (0.071, 0.35)	8	0.90 (0.37, 1.1)	0.002
Week 4	46	0.19 (0.084, 0.46)	7	0.75 (0.4, 2)	0.005
Week 8	46	0.24 (0.097, 0.5)	8	0.89 (0.475, 1.55)	0.014
Week 12	46	0.19 (0.076, 0.52)	7	0.85 (0.7, 3.8)	<0.001
Week 24	46	0.24 (0.12, 0.53)	6	1.7 (0.92, 2.2)	0.010

Abbreviation: IQR, interquartile range.

^a Patient numbers decrease over time either because patients discontinued the study or missed the sample collection period.