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. Author manuscript; available in PMC: 2023 Sep 1.
Published in final edited form as: Neurobiol Aging. 2022 May 26;117:107–116. doi: 10.1016/j.neurobiolaging.2022.05.007

Table 1.

Comparison of a-MDD and LLD cases with cases with no MDD.

a-MDD (n = 54) LLD (n = 80) no MDD (n = 607) a-MDD × no MDD p LLD × no MDD p

Age at death (years), mean (SD)a 63.6 (10.8) 76.4 (8.8) 72.3 (11.7) < 0.001 0.001
Education (years), mean (SD)a 4.4 (3.0) 3.8 (3.3) 4.6 (3.8) 0.79 0.08
Women, nb (%) 32 (59.3%) 45 (56.3%) 277 (45.6%) 0.054 0.07
Ethnicity white, nb (%) 37 (68.5%) 55 (68.8%) 420 (69.2%) 0.92 0.67
CDR = 0, nb (%) 41 (75.9%) 60 (75.0%) 519 (85.5%) 0.061 0.015
Alcohol misuse, nb (%) 12 (25.0%) 16 (20.5%) 100 (18.5%) 0.27 0.64
Smoking, nb (%) 28 (52.8%) 32 (40.5%) 238 (41.5%) 0.11 0.86
Hypertension, nb (%) 42 (77.8%) 53 (66.3%) 410 (68.4%) 0.16 0.69
Diabetes mellitus, nb (%) 9 (16.7%) 21 (26.3%) 168 (28.0%) 0.07 0.74
Dyslipidemia, nb (%) 5 (9.3%) 3 (3.8%) 68 (11.2%) 0.64 0.042

Data are presented as means (SD) and for categorical values as the number of cases, and percentage (%) when indicated.

Key: a-MDD, adult-onset major depressive disorder; CDR, Clinical Dementia Rating scale; LLD, late life depression; MDD, major depressive disorder; SD, standard deviation.

a

Mann-Whitney test.

b

Qui-square test.