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. 2023 Feb 27;18(2):e0282462. doi: 10.1371/journal.pone.0282462

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© 2023 Barham et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 5 — (A) ASM/A images. (B) ASM/S images. (C) ASM/A³, PASM/A³ and ASM/S³ images. Phantoms used were bio-phantoms of Jurkat cells and polyethylene glycol phantoms. Vertical bar represents relative values of DK image and ASM images, which were modified for their PS values to become 5,000. Error bar represents standard deviation for each value. ⁺P<0.05 and ^‡P<0.01, Dunn’s method added to Kruskal-Wallis test for comparison between values of DK image and each ASM image. **P<0.01 and NS, not significant by Kruskal-Wallis test for comparison among the values of ASM images. ADC, apparent diffusion coefficient; ASM, ADC subtraction method; PS, physiological saline; LC, low-cellularity; HC, high-cellularity; DKI, diffusion kurtosis imaging; ASM/A^x, ASM division by ADC x times; ASM/S^x, ASM division by standard deviation x times; PASM/A³, positive ASM division by ADC three times.