Table 2.
Top 10 important predictors of the prediction models for impaired glucose metabolism.
| Rank | LR with LASSO | XGBoost | Random forest |
|---|---|---|---|
| 1 | Normal range of blood glucose level within 1 year before diagnosis | Normal range of blood glucose level within 1 year before diagnosis | Normal range of blood glucose level within 1 year before diagnosis |
| 2 | Normal range of blood calcium level within 1 year before diagnosis | Measurement of blood aspartate aminotransferase level within 1 year before diagnosis | Measurement of blood alanine aminotransferase level within 1 year before diagnosis |
| 3 | Measurement of urinalysis within 1 month before diagnosis | Measurement of blood triglyceride within 1 year before diagnosis | Measurement of blood cholesterol level within 1 year before diagnosis |
| 4 | Measurement of blood platelet within 1 year before diagnosis | NSAIDs prescription within 1 month before diagnosis | Measurement of blood alanine aminotransferase level within 1 year before diagnosis |
| 5 | CT within 1 month before diagnosis | Measurement of urinalysis within 1 year before diagnosis | Measurement of blood aspartate aminotransferase level within 1 year before diagnosis |
| 6 | Measurement of C reactive protein within 1 month before diagnosis | Antipsychotics prescription within 1 year before diagnosis | Normal range of blood bilirubin level within 1 year before diagnosis |
| 7 | Drugs for peptic ulcer prescription at diagnosis | SSRI prescription at diagnosis | Measurement of uric acid level within 1 year before diagnosis |
| 8 | Measurement of blood cholesterol level within 1 year before diagnosis | HMG CoA reductase inhibitors prescription within 1 month before diagnosis | Measurement of creatine level within 1 year before diagnosis |
| 9 | Antipsychotics prescription within 1 year before diagnosis | Measurement of blood hepatitis B virus test within 1 month before diagnosis | Measurement of blood albumin level within 1 year before diagnosis |
| 10 | Normal range of blood aspartate aminotransferase level within 1 year before diagnosis | Haloperidol prescription at diagnosis | Measurement of blood protein level within 1 year before diagnosis |
Note: The color in the table means the category of features (orange: laboratory test, green: image test, and blue: drug exposure).
Abbreviations: CT, computed tomography; LASSO, least absolute shrinkage and selection operator; LR, logistic regression; NSAID, non-steroidal anti-inflammatory drugs; SSRI, selective serotonin reuptake inhibitor; XGBoost, extreme gradient boosting.