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. 2023 Feb 23;12(1):2178241. doi: 10.1080/22221751.2023.2178241

Figure 4.

Figure 4.

Potent synergism of EK1 combined with WT-RBD-immunized mouse sera or BA.2-convalescent sera against Omicron subvariants. (a) WT-RBD immunization protocols. (b) Efficacy of WT-RBD-immunized mouse serum against SARS-CoV-2 WT and Omicron subvariants. (c–h), Synergism of EK1 and WT-RBD-immunized mouse sera against WT SARS-CoV-2 (c) BA.2.12.1 (d) BA.4/BA.5 (e) BA.4.6 (f) BA.2.75 (g) and BF.7 (h). Samples were tested in triplicate, and the experiment was repeated once. Data from a representative experiment are presented in mean ± SD. Asterisks indicate significant differences (***P < 0.001, **P < 0.01).