Table 3. The correlation of tumor DNA mutation, cfDNA mutation, single peritoneal metastasis and single distant lymphatic metastasis.

Genetic mutation	Tumor DNA			cfDNA
	Peritoneum n = 27 n (%)	Distant LM n = 21 n (%)	P value	Peritoneum n = 27 n (%)	Distant LM n = 21 n (%)	P value
CREBBP	2 (7.4)	2 (9.5)	0.792	1 (3.7)	1 (4.8)	0.856
TP53	11 (40.7)	8 (38.1)	0.853	3 (11.1)	0	0.115
ARID1A	11 (40.7)	7 (33.3)	0.599	4 (14.8)	3 (14.3)	0.959
BCOR	1 (3.7)	4 (19.0)	0.084	0	1 (4.8)	0.252
CTNNB1	1 (3.7)	0	0.373	0	0
KMT2D	10 (37.0)	6 (28.6)	0.537	8 (29.6)	2 (9.5)	0.089
RNF43	1 (3.7)	1 (4.8)	0.856	0	0
APC	3 (11.1)	0	0.115	2 (7.4)	0	0.203
FAT4	3 (11.1)	7 (33.3)	0.060	2 (7.4)	6 (28.6)	0.051
KMT2C	8 (29.6)	6 (28.6)	0.936	4 (14.8)	2 (9.5)	0.582
ABCA10	5 (18.5)	2 (9.5)	0.381	5 (18.5)	2 (9.5)	0.381
MUC6	2 (7.4)	2 (9.5)	0.792	1 (3.7)	2 (9.5)	0.409
KRAS	0	0		0	0
SMAD4	1 (3.7)	0	0.373	1 (3.7)	0	0.373
PIK3CA	3 (11.1)	1 (4.8)	0.430	0	0
BNC2	2 (7.4)	2 (9.5)	0.792	1 (3.7)	2 (9.5)	0.409
PLB1	3 (11.1)	5 (23.8)	0.242	1 (3.7)	5 (23.8)	0.037
MACF1	7 (25.9)	4 (19.0)	0.574	5 (18.5)	3 (14.3)	0.696
ERBB3	4 (14.8)	3 (14.3)	0.959	2 (7.4)	2 (9.5)	0.792
CDH1	4 (14.8)	2 (9.5)	0.582	3 (11.1)	2 (9.5)	0.858
RASA1	2 (7.4)	1 (4.8)	0.707	1 (3.7)	0	0.373
PREX2	2 (7.4)	1 (4.8)	0.707	0	0
EYA4	1 (3.7)	1 (4.8)	0.856	1 (3.7)	0	0.373
LRP18	6 (22.2)	5 (23.8)	0.897	3 (11.1)	4 (19.0)	0.440
FAM46D	1 (3.7)	1 (4.8)	0.856	0	1 (4.8)	0.252
SMAD2	1 (3.7)	2 (9.5)	0.409	0	0
RHOA	0	1 (4.8)	0.252	0	0
SOHLH2	2 (7.4)	1 (4.8)	0.707	1 (3.7)	1 (4.8)	0.856
CNGA4	0	0		0	0

Abbreviations: cfDNA: cell-free DNA; LM: lymphatic metastasis.