Table 1. Baseline characteristics for the CLUE II population, by age acceleration vs. deceleration.
| Overall | AA_Hannum | AA_Horvath | AA_Pheno | ||||
| Acceleration | Deceleration | Acceleration | Deceleration | Acceleration | Deceleration | ||
| N | 416 | 210 | 203 | 208 | 205 | 220 | 193 |
| Case | 208 (50.0%) | 104 (49.5%) | 101 (49.8%) | 99 (47.6%) | 107 (52.2%) | 114 (51.8%) | 91 (47.2%) |
| Control | 208 (50.0%) | 106 (50.5%) | 102 (50.2%) | 109 (52.4%) | 98 (47.8%) | 106 (48.2%) | 102 (52.8%) |
| Age (yrs), mean (SD) | 57.1 (10.0) | 57.3 (9.3) | 56.6 (10.5) | 57.1 (8.9) | 56.9 (11.0) | 56.8 (9.4) | 57.2 (10.7) |
| Female, n (%) | 226 (54.3%) | 90 (42.9%) | 133 (65.5%) | 97 (46.6%) | 127 (62.0%) | 108 (49.1%) | 115 (59.6%) |
| Time Difference (yrs), mean (SD) | 14.9 (7.9) | 13.9 (7.3) | 16.2 (8.2) | 14.5 (7.6) | 15.4 (8.1) | 14.7 (7.7) | 15.3 (8.2) |
| Smoking status | |||||||
| Never | 44 (10.6%) | 23 (11.0%) | 21 (10.3%) | 28 (13.5%) | 16 (7.8%) | 22 (10.0%) | 21 (10.9%) |
| Former | 160 (38.5%) | 86 (41.0%) | 73 (36.0%) | 80 (38.5%) | 79 (38.5%) | 86 (38.6%) | 74 (38.3%) |
| Current | 212 (50.9%) | 101 (48.0%) | 109 (53.7%) | 100 (48.0%) | 110 (53.7%) | 112 (51.4%) | 98 (50.8%) |
| BMI (kg/m2), mean (SD) | 26.1 (4.4) | 26.2 (4.3) | 26.1 (4.5) | 26.7 (4.5) | 25.6 (4.2) | 26.0 (4.4) | 26.2 (4.4) |
| Normal and underweight | 179 (43.0%) | 87 (41.4%) | 90 (44.3%) | 76 (36.5%) | 100 (48.8%) | 94 (42.3%) | 82 (42.5%) |
| Overweight | 171 (41.1%) | 89 (42.4%) | 81 (39.9%) | 91 (43.8%) | 80 (39.0%) | 95 (43.2%) | 76 (39.4%) |
| Obese | 66 (15.9%) | 34 (16.2%) | 32 (15.8%) | 41 (19.7%) | 25 (12.2%) | 31 (14.4%) | 35 (18.1%) |
Abbreviations: SD: standard deviation; AA: age acceleration; BMI: body mass index.