Table 3. Comparison of pre- and post-rehabilitation outcome measures.a .
| Variable | Study group (n = 21) |
Control group (n = 21) |
F | p‡ | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Before PR | After PR | ∆ | F | p† | Before PR | After PR | ∆ | F | p† | |||
| PFT FEV1 (% predicted) FVC (% predicted) FEV1/FVC |
85.05 ± 4.44 83.94 ± 3.76 83.47 ± 3.92 |
89.63 ± 4.96 90.94 ± 4.11 86.76 ± 4.05 |
4.57 ± 2.41 7.01 ± 2.72 3.28 ± 2.73 |
3.586 6.619 1.445 |
0.066 0.014 0.237 |
80.00 ± 4.44 77.47 ± 3.76 86.15 ± 3.92 |
84.68 ± 4.96 83.57 ± 4.11 86.84 ± 4.05 |
4.68 ± 2.41 6.10 ± 2.72 0.68 ± 2.73 |
3.753 5.035 0.063 |
0.061 0.031 0.804 |
0.603 1.476 0.234 |
0.443 0.232 0.632 |
| mMRC scale | 2.63 ± 0.33 | 1.21 ± 0.300 | 1.42 ± 0.24 | 33.38 | < 0.001 | 2.31 ± 0.33 | 1.84 ± 0.30 | 0.474 ± 0.24 | 3.710 | 0.062 | 0.143 | 0.708 |
| Six-minute walk test 6MWD ∆Dyspnea (mBORG) ∆Leg fatigue (mBORG) |
378.1 ± 28.9 2.368 ± 0.38 2.158 ± 0.27 |
440.9 ± 25.8 1.368 ± 0.31 1.263 ± 0.29 |
62.8 ± 15.1 1.00 ± 0.31 0.89 ± 0.30 |
17.222 10.09 8.862 |
< 0.001 0.003 0.005 |
325.1 ± 28.9 2.051 ± 0.38 1.789 ± 0.27 |
381.7 ± 25.8 2.158 ± 0.31 1.787 ± 0.29 |
56.6 ± 15.1 0.10 ± 0.31 0.02 ± 0.01 |
14.013 0.112 0.001 |
0.001 0.740 0.998 |
1.671 0.336 0.934 |
0.204 0.565 0.340 |
| Muscle strength Right biceps Left biceps Right deltoid Left deltoid Right quadriceps Left quadriceps |
4.737 ± 0.12 4.737 ± 0.12 4.422 ± 0.15 4.474 ± 0.14 4.737 ± 0.09 4.737 ± 0.09 |
4.947 ± 0.03 4.947 ± 0.03 4.895 ± 0.07 4.895 ± 0.11 5.00 ± 0.03 5.00 ± 0.00 |
0.211 ± 0.12 0.211 ± 0.12 0.474 ± 0.12 0.421 ± 0.11 0.263 ± 0.08 0.105 ± 0.13 |
3.097 3.064 13.75 14.58 8.654 7.627 |
0.087 0.089 0.001 0.001 0.006 0.009 |
4.572 ± 0.12 4.522 ± 0.12 4.474 ± 0.15 4.368 ± 0.14 4.842 ± 0.09 4.842 ± 0.09 |
5.00 ± 0.037 5.00 ± 0.037 4.842 ± 0.07 4.632 ± 0.11 4.947 ± 0.03 5.00 ± 0.00 |
0.421 ± 0.12 0.474 ± 0.12 0.368 ± 0.120 0.263 ± 0.11 0.105 ± 0.08 0.001 ± 0.01 |
12.387 15.51 8.321 5.696 1.385 2.746 |
0.001 < 0.001 0.007 0.001 0.247 0.106 |
0.298 0.664 0.062 0.250 0.610 0.610 |
0.589 0.421 0.805 0.620 0.440 0.440 |
| SGRQ Symptoms Activity Impact Total |
40.78 ± 6.19 62.56 ± 4.85 41.46 ± 5.69 47.77 ± 4.97 |
35.25 ± 5.23 49.06 ± 6.32 30.05 ± 5.77 36.67 ± 5.45 |
−5.52 ± 3.61 −13.49 ± 4.70 −11.41 ± 3.42 −11.09 ± 2.87 |
2.340 8.244 11.07 14.94 |
0.135 0.007 0.002 <0.001 |
36.55 ± 6.19 65.19 ± 4.85 47.24 ± 5.69 50.91 ± 4.97 |
31.38 ± 5.23 52.95 ± 6.32 33.3 ± 5.77 39.03 ± 5.45 |
−5.202 ± 3.61 −12.24 ± 4.70 −13.86 ± 3.42 −11.88 ± 2.87 |
2.070 6.783 16.34 17.14 |
0.159 0.013 < 0.001 < 0.001 |
0.229 0.148 0.516 0.200 |
0.635 0.703 0.477 0.657 |
| SF-36 Physical functioning Social functioning Role-physical Role-emotional General health Mental health Bodily pain Vitality |
52.36 ± 6.25 32.23 ± 6.22 15.78 ± 6.90 24.36 ± 7.12 57.89 ± 5.53 63.57 ± 4.72 48.94 ± 7.32 50.00 ± 4.98 |
66.84 ± 6.97 68.42 ± 6.10 50.00 ± 8.84 50.63 ± 8.57 62.63 ± 5.81 69.21 ± 5.76 78.15 ± 5.22 62.63 ± 5.76 |
14.47 ± 6.08 36.18 ± 6.13 34.21 ± 9.11 26.26 ± 8.78 4.737 ± 4.34 5.631 ± 3.63 29.21 ± 6.03 12.63 ± 4.72 |
5.653 34.79 14.08 8.937 1.187 2.395 23.45 7.134 |
0.023 < 0.001 0.001 0.005 0.283 0.130 < 0.001 0.011 |
52.89 ± 6.25 44.07 ± 6.22 22.36 ± 6.90 27.94 ± 7.21 53.94 ± 5.53 58.10 ± 4.72 59.47 ± 7.32 47.10 ± 4.98 |
59.47 ± 6.95 57.23 ± 6.10 43.42 ± 8.84 47.10 ± 8.57 57.36 ± 5.81 64.0 ± 5.76 73.50 ± 5.22 53.15 ± 5.76 |
6.579 ± 6.08 13.15 ± 6.13 21.05 ± 9.11 19.15 ± 8.78 3.421 ± 4.34 5.895 ± 0.11 14.02 ± 6.03 6.05 ± 4.72 |
1.168 4.601 5.333 4.755 0.619 2.624 5.408 1.638 |
0.287 0.039 0.027 0.036 0.436 0.068 0.026 0.209 |
0.004 1.812 0.454 0.123 0.254 0.672 1.033 0.169 |
0.953 0.187 0.505 0.728 0.617 0.418 0.316 0.684 |
| HADS Anxiety Depression |
6.263 ± 1.04 5.895 ± 0.98 |
5.105 ± 1.10 6.00 ± 1.10 |
1.15 ± 0.070 0.10 ± 0.58 |
2.263 0.033 |
0.141 0.857 |
7.158 ± 1.04 7.260 ± 0.09 |
7.737 ± 1.10 7.158 ± 1.10 |
0.57 ± 0.45 0.10 ± 0.58 |
0.566 0.033 |
0.457 0.857 |
0.370 0.968 |
0.547 0.332 |
PR: pulmonary rehabilitation; PFT: pulmonary function testing; mMRC: modified Medical Research Council; 6MWD: six-minute walk distance; mBORG: modified Borg scale; SGRQ: Saint George’s Respiratory Questionnaire; SF-36: Medical Outcomes Study 36-item Short-Form Health Survey; and HADS: Hospital Anxiety and Depression Scale. aData presented as mean ± standard error of the mean. Repeated-measures ANOVA. †Within-group differences. ‡Comparison of baseline values in the groups.