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. 2022 Dec 15;49(1):e20220107. doi: 10.36416/1806-3756/e20220107

Table 4. Group effect, time effect, and group-time effect on the outcome variables.

Variable Group effect Time effect Group-time effecta Partial h2 Statistical power
F p F p F p
PFT
FEV1 (% predicted)
FVC (% predicted)
FEV1/FVC

2.257
1.745
0.068

0.142
0.195
0.796

7.339
11.60
1.055

0.010
0.002
0.311

0.001
0.054
0.453

0.976
0.817
0.505

0.001
0.001
0.012

0.050
0.056
0.100
mMRC scale 0.143 0.708 17.05 < 0.001 7.420 0.010 0.171 0.755
Six-minute walk test
6MWD
Dyspnea (mBORG)
Leg fatigue (mBORG)

2.257
0.281
0.055

0.142
0.599
0.816

31.152
4.039
4.431

< 0.001
0.052
0.042

0.083
6.163
4.431

0.775
0.018
0.042

0.002
0.146
0.110

0.059
0.676
0.535
Muscle strength
Right biceps
Left biceps
Right deltoid
Left deltoid
Right quadriceps
Left quadriceps

0.298
0.664
0.001
1.208
0.107
0.610

0.589
0.421
0.997
0.279
0.745
0.440

13.93
16.18
21.73
19.25
8.486
9.763

0.001
< 0.001
< 0.001
< 0.001
0.006
0.004

1.544
2.394
0.340
1.025
1.558
0.610

0.221
0.131
0.564
0.318
0.220
0.440

0.041
0.062
0.009
0.028
0.041
0.017

0.228
0.325
0.088
0.167
0.229
0.118
SGRQ
Symptoms
Activity
Impact
Total

0.274
0.203
0.347
0.150

0.604
0.655
0.559
0.701

4.406
14.99
27.16
32.05

0.043
< 0.001
< 0.001
< 0.001

0.004
0.036
0.255
0.038

0.949
0.851
0.616
0.847

0.001
0.001
0.007
0.001

0.050
0.054
0.078
0.054
SF-36
Physical functioning
Social functioning
Role-physical
Role-emotional
General health
Mental health
Bodily pain
Vitality

0.170
0.002
0.001
0.001
0.386
0.584
0.137
0.816

0.683
0.966
0.998
0.998
0.538
0.450
0.713
0.372

5.980
32.34
18.37
13.36
1.761
5.016
25.69
7.805

0.019
< 0.001
< 0.001
0.001
0.193
0.031
< 0.001
0.008

0.841
7.045
1.042
0.327
0.046
0.003
3.169
0.968

0.365
0.012
0.314
0.571
0.832
0.960
0.083
0.332

0.023
0.164
0.028
0.009
0.001
0.001
0.081
0.026

0.145
0.733
0.168
0.086
0.055
0.050
0.410
0.160
HADS
Anxiety
Depression

1.549
0.792

0.221
0.379

0.283
0.001

0.598
0.998

2.546
0.065

0.119
0.800

0.066
0.002

0.342
0.057

PFT: pulmonary function testing; mMRC: modified Medical Research Council; 6MWD: six-minute walk distance; mBORG: modified Borg scale; SGRQ: Saint George’s Respiratory Questionnaire; SF-36: Medical Outcomes Study 36-item Short-Form Health Survey; and HADS: Hospital Anxiety and Depression Scale. aGroup-time effect is also known as comparison of ∆ values. Repeated-measures ANOVA.