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. Author manuscript; available in PMC: 2023 Nov 1.
Published in final edited form as: Mol Genet Metab. 2022 Oct 5;137(3):283–291. doi: 10.1016/j.ymgme.2022.09.011

Table 1.

Comparison of putative animal models of PKAN and their fidelity to the human disease.

graphic file with name nihms-1857719-t0004.jpg
*

dopamine metabolism is perturbed, but clinical neurological features are absent; ‘+’ means present; ‘-’means absent; ‘n’ before a gene name refers to neuronal-specific knock-out; N/A = not assessed; ˆ- see text for detailed discussion.