Table 3.
Association between rs6587666 and eczema by additive model in SCAALA Brazilian cohort.
Chr | Gene | SNP | Geno | Non-eczema | Eczema | OR (95% CI) | P-value* |
---|---|---|---|---|---|---|---|
1q21 | FLG | rs6587666 | C/C | 609 (60.3%) | 96 (70.1%) | 0.66 (0.47–0.93) | 0.017 |
T/C | 349 (34.5%) | 37 (27%) | |||||
T/T | 52 (5.2%) | 4 (2.9%) |
aChr, Chromosome; bSNP, single nucleotide polymorphism; cADD, additive; dGeno, genotype; eOR, Odds ratio; fCI, confidence interval. *Adjusted by gender, age, helminthic infection, population structure, and asthma symptoms. *P-value considering adaptative permutations using the additive model.