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. 2023 Feb 10;9(2):e13659. doi: 10.1016/j.heliyon.2023.e13659

Table 3.

Association between rs6587666 and eczema by additive model in SCAALA Brazilian cohort.

Chr Gene SNP Geno Non-eczema Eczema OR (95% CI) P-value*
1q21 FLG rs6587666 C/C 609 (60.3%) 96 (70.1%) 0.66 (0.47–0.93) 0.017
T/C 349 (34.5%) 37 (27%)
T/T 52 (5.2%) 4 (2.9%)

aChr, Chromosome; bSNP, single nucleotide polymorphism; cADD, additive; dGeno, genotype; eOR, Odds ratio; fCI, confidence interval. *Adjusted by gender, age, helminthic infection, population structure, and asthma symptoms. *P-value considering adaptative permutations using the additive model.