Table 2.
Risk for stillbirth by demographics and maternal characteristics
| Characteristic | Crude |
COVID-19 infection |
COVID-19 infection |
|||
|---|---|---|---|---|---|---|
| 0–20 gestational wk, adjusted |
21–27 gestational wk, adjusted |
|||||
| OR | 95% CI | OR | 95% CI | OR | 95% CI | |
| Age group | ||||||
| 15–19 | 1.21 | (0.92–1.60) | 1.07 | (0.79–1.44) | 1.15 | (0.85–1.55) |
| 20–24 | 1.19a | (1.04–1.36)a | 1.03 | (0.88–1.21) | 1.02 | (0.86–1.21) |
| 25–29 | 1.06 | (0.95–1.19) | ref. | ref. | ref. | ref. |
| 30–34 | 0.82 | (0.73–0.92) | 0.87 | (0.76–1.00) | 0.87 | (0.75–1.00) |
| 35–39 | 0.95 | (0.84–1.08) | 0.96 | (0.83–1.12) | 0.92 | (0.79–1.09) |
| 40–44 | 1.10 | (0.89–1.36) | 1.04 | (0.82–1.32) | 0.99 | (0.77–1.27) |
| 45–49 | 1.84a | (1.04–3.25)a | 1.88a | (1.05–3.37)a | 1.87a | (1.02–3.42)a |
| Race and ethnicity | ||||||
| White | 0.70a | (0.63–0.77)a | ref. | ref. | ref. | ref. |
| Black | 1.97a | (1.77–2.20)a | 1.98a | (1.74–2.25)a | 1.99a | (1.74–2.27)a |
| Hispanic/Latino | 0.89 | (0.78–1.01) | 1.14 | (0.98–1.32) | 1.14 | (0.97–1.33) |
| Asian | 0.59a | (0.44–0.78)a | 0.76 | (0.56–1.02) | 0.73 | (0.53–1.00) |
| NHOPI | 2.60a | (1.29–5.24)a | 2.18 | (0.90–5.30) | 2.80a | (1.24–6.33)a |
| Multiracial | 1.27 | (0.75–2.16) | 1.44 | (0.81–2.56) | 1.17 | (0.60–2.26) |
| Other/unknown | 1.06 | (0.88–1.27) | 1.31a | (1.07–1.60)a | 1.36a | (1.11––1.68)a |
| COVID-19 infection: 0–20 gestational wk | 1.79a | (1.28–2.52)a | 1.75a | (1.25–2.46)a | — | — |
| COVID-19 infection: 21–27 gestational wk | 2.28a | (1.67–3.25)a | — | — | 2.09a | (1.49–2.93)a |
| Obesity/overweight | 1.20a | (1.08–1.33)a | 1.07 | (0.96–1.20) | 1.07 | (0.95–1.20) |
| Hypertension | 1.31a | (1.17–1.46)a | 1.16a | (1.03–1.31)a | 1.18a | (1.04–1.34)a |
| Diabetes mellitus | 1.04 | (0.89–1.20) | 0.95 | (0.81–1.12) | 1.00 | (0.85–1.18) |
| COPD | 1.70 | (0.63–4.58) | 1.15 | (0.42–3.19) | 0.87 | (0.27–2.80) |
| ARDS/ARF | 4.42a | (2.98–6.55)a | 3.50a | (2.15–5.71)a | 4.26a | (2.69–6.73)a |
| Congestive heart failure | 2.33a | (1.37–3.97)a | 1.55 | (0.88–2.72) | 1.33 | (0.72–2.45) |
| Myocardial infarction | 2.24 | (0.92–5.42) | 1.60 | (0.64–3.97) | 1.76 | (0.71–4.37) |
| HIV/AIDS | 1.32 | (0.68–2.55) | 1.02 | (0.51–2.05) | 1.22 | (0.63–2.37) |
| Placental abruption | 4.94a | (3.93–6.21)a | 4.46a | (3.50–5.67)a | 4.45a | (3.46–5.72)a |
ARDS/ARF, acute respiratory distress syndrome or acute respiratory failure; CI, confidence interval; COPD, chronic obstructive pulmonary disease; NHOPI, Native Hawaiian and Other Pacific Islander; OR, odds ratio; ref., reference interval.
Lyu. Stillbirth and different maternal SARS-CoV-2 infection time. Am J Obstet Gynecol 2023.
Significant difference compared with all levels or reference levels.