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. 2023 Feb 28. Online ahead of print. doi: 10.1016/j.ajog.2023.02.022

Table 2.

Risk for stillbirth by demographics and maternal characteristics

Characteristic Crude
COVID-19 infection
COVID-19 infection
0–20 gestational wk, adjusted
21–27 gestational wk, adjusted
OR 95% CI OR 95% CI OR 95% CI
Age group
 15–19 1.21 (0.92–1.60) 1.07 (0.79–1.44) 1.15 (0.85–1.55)
 20–24 1.19a (1.04–1.36)a 1.03 (0.88–1.21) 1.02 (0.86–1.21)
 25–29 1.06 (0.95–1.19) ref. ref. ref. ref.
 30–34 0.82 (0.73–0.92) 0.87 (0.76–1.00) 0.87 (0.75–1.00)
 35–39 0.95 (0.84–1.08) 0.96 (0.83–1.12) 0.92 (0.79–1.09)
 40–44 1.10 (0.89–1.36) 1.04 (0.82–1.32) 0.99 (0.77–1.27)
 45–49 1.84a (1.04–3.25)a 1.88a (1.05–3.37)a 1.87a (1.02–3.42)a
Race and ethnicity
 White 0.70a (0.63–0.77)a ref. ref. ref. ref.
 Black 1.97a (1.77–2.20)a 1.98a (1.74–2.25)a 1.99a (1.74–2.27)a
 Hispanic/Latino 0.89 (0.78–1.01) 1.14 (0.98–1.32) 1.14 (0.97–1.33)
 Asian 0.59a (0.44–0.78)a 0.76 (0.56–1.02) 0.73 (0.53–1.00)
 NHOPI 2.60a (1.29–5.24)a 2.18 (0.90–5.30) 2.80a (1.24–6.33)a
 Multiracial 1.27 (0.75–2.16) 1.44 (0.81–2.56) 1.17 (0.60–2.26)
 Other/unknown 1.06 (0.88–1.27) 1.31a (1.07–1.60)a 1.36a (1.11––1.68)a
COVID-19 infection: 0–20 gestational wk 1.79a (1.28–2.52)a 1.75a (1.25–2.46)a
COVID-19 infection: 21–27 gestational wk 2.28a (1.67–3.25)a 2.09a (1.49–2.93)a
Obesity/overweight 1.20a (1.08–1.33)a 1.07 (0.96–1.20) 1.07 (0.95–1.20)
Hypertension 1.31a (1.17–1.46)a 1.16a (1.03–1.31)a 1.18a (1.04–1.34)a
Diabetes mellitus 1.04 (0.89–1.20) 0.95 (0.81–1.12) 1.00 (0.85–1.18)
COPD 1.70 (0.63–4.58) 1.15 (0.42–3.19) 0.87 (0.27–2.80)
ARDS/ARF 4.42a (2.98–6.55)a 3.50a (2.15–5.71)a 4.26a (2.69–6.73)a
Congestive heart failure 2.33a (1.37–3.97)a 1.55 (0.88–2.72) 1.33 (0.72–2.45)
Myocardial infarction 2.24 (0.92–5.42) 1.60 (0.64–3.97) 1.76 (0.71–4.37)
HIV/AIDS 1.32 (0.68–2.55) 1.02 (0.51–2.05) 1.22 (0.63–2.37)
Placental abruption 4.94a (3.93–6.21)a 4.46a (3.50–5.67)a 4.45a (3.46–5.72)a

ARDS/ARF, acute respiratory distress syndrome or acute respiratory failure; CI, confidence interval; COPD, chronic obstructive pulmonary disease; NHOPI, Native Hawaiian and Other Pacific Islander; OR, odds ratio; ref., reference interval.

Lyu. Stillbirth and different maternal SARS-CoV-2 infection time. Am J Obstet Gynecol 2023.

a

Significant difference compared with all levels or reference levels.