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. 2023 Feb 28;84:129211. doi: 10.1016/j.bmcl.2023.129211

Table 1.

Inhibition of viral infectivity. BHK-21 cells were infected with HCoV-OC43 (MOI = 0.1), and treated with compounds (10 μM) for 3 days. The table shows log10 reduction in TCID50/ml compared to the DMSO (negative) control (n = 3; mean ± standard error). Significance of differences was determined by ANOVA with Tukey’s multiple comparisons; ns, not significant; *, p ≤ 0.05; **, p ≤ 0.001.

Compound log10 reduction in infectivity (mean ± SEM)
xanthone 2.04±0.58
mangiferin 3.00±0.60 **
5 2.50±0.70 *
6 2.00±0.37
7 1.95±0.28 **
8 2.20±0.23 **
10 2.42±0.56
11 2.79±0.48 *
12 2.67±0.51 *
13 2.67±0.42 *
14 2.38±0.47
15 1.95±0.25 **
16 (R = H) 2.45±0.19 **