Table 2.

Results of property predictions for compounds synthesised.⁴⁰

Compound	miLogP (<5)	HBA (≤10)	HBD (≤5)	Mr [Da] (〈500)	No. of violations of the Rule of Five	PSA [Å2] (<140 Å2)	No. of rotatable bonds	No. of violations of the Rule of Three
xanthone	3.57	2	0	196.21	0	30.21	0	1
mangiferin	−0.16	11	8	422.34	2	201.27	2	3
5	2.78	4	2	228.20	0	70.67	0	1
6	2.51	5	3	244.20	0	90.89	0	1
7	2.81	4	2	228.20	0	70.67	0	1
8	2.80	4	2	228.20	0	70.67	0	1
10	3.20	4	2	242.23	0	70.67	0	2
11	3.20	4	2	242.23	0	70.67	0	2
12	2.81	5	2	258.23	0	79.90	1	1
13	2.81	5	2	258.23	0	79.90	1	1
14	1.94	4	2	246.19	0	70.67	0	1
15	2.30	5	4	246.22	0	97.98	2	2
16 (R = H)	2.77	4	3	230.22	0	77.75	2	1