Skip to main content
. 2023 Feb 14;14:1075250. doi: 10.3389/fpsyt.2023.1075250

FIGURE 1.

FIGURE 1

Results of the EWAS of CUD assessing N = 654,448 cytosine-phosphate-guanine (CpG) sites in N = 42 post-mortem human brain samples from Brodmann area 9 (BA9). (A) In the Manhattan plot, the 10 CpG sites displaying the strongest association with CUD status were highlighted in blue and were annotated to gene name if available. The 20 CUD-associated DMRs are highlighted in orange. The solid blue line depicts epigenome-wide significance (p < 7.64e–08). (B) EWAS summary statistics for the 10 CpG sites showing the strongest association with CUD status.