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. 2022 Dec 16;5(4):100651. doi: 10.1016/j.jhepr.2022.100651

Fig. 6.

Fig. 6

Markers of liver fibrosis are reduced in response to S217879 treatment in DIO NASH mice.

(A) Col1A1- and αSMA-stained liver sections at termination (n = 14 per group). (B) Quantification of Col1A1- and αSMA-positive areas by morphometry. Liver hydroxyproline levels quantified after extraction and centrifugation using a colorimetric assay. Data expressed as mean ± SEM. Significant differences were analyzed using Student’s t test. ∗∗∗p <0.001 and ∗∗p <0.01: S217879-treated vs. vehicle.