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. 2021 Nov 15;25(1):3–17. doi: 10.1007/s11307-021-01665-2

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5. — Label free in vivo imaging of mouse kidney. a Anesthetized mouse with one kidney being elevated from the body and clamped between two tongue depressors, beneath the 2.2 mm TPME probe (red arrow); b SHG (in green) and TPEF (in red) raw image of respectively the collagen of the capsule and the intracellular flavins of epithelial cells of the kidney tubules, c same as in (b) but with a larger FOV. Scale bars = 50 μm [16].