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. 2022 Sep 19;25(1):36–45. doi: 10.1007/s11307-022-01772-8

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Fig. 6 — Activatable fluorescence probes. A Enzyme-activable probes allow for fluorescence signal to emit only in the presence of specific enzymatic activity. B An alternative strategy allows for fluorescence activation after incorporation of the agent by surface molecule binding and lysosome phagocytosis by the targeted cancer cell.