Table 1.

Search strategy and selection criteria

Sources	Pubmed (https://www.ncbi.nlm.nih.gov/pubmed)
Period of time covered	From January 1979 until October 2022
Search terms	“Artificial intelligence”, “Chronic active lesions”, “Cortical lesions”, Deep learning”, “Diagnostic Criteria”, “Differential Diagnosis”, “Inflammation”, “Iron Rim Lesions”, “Leptomeningeal Inflammation”, “Lesion/s”, “MRI”, “Machine Learning”, “McDonald criteria”, “MOGAD”, “Multiple Sclerosis”, “NMOSD”, “Paramagnetic Rim Lesions”, “Primary Progressive”, “Spinal Cord”, “Subpial Demyelination”, “White Matter”
Selection criteria and review preparation	1. Only papers published in English 2. The final reference list was generated with the consensus of all co-authors of this review on the basis of originality and relevance to the broad scope of this review, with a focus on the most recent articles published in the last three years 3. Experts provided a summary during the meeting of the main findings related to specific topics of the review. For each topic, a group consensus was reached and summarized in a first draft, which was circulated among the co-authors for further critical discussion and revision. The review represents the final conclusions reached by co-authors