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. 2023 Feb 27;13:3366. doi: 10.1038/s41598-023-29591-z

Table 2.

Intra-observer repeatability for patients with myocardial infarction (infarct), hypertrophic cardiomyopathy (non-fibrosis) or dilated cardiomyopathy.

Myocardial infarction (n = 20) First measurement Second measurement Mean difference P value LCC (95% CI) Bland–Altman (95% LoA) CoV (%)
 Native T1 (ms) infarct 1395 ± 72 [1246–1501] 1391 ± 74 [1241–1485] −3.8 0.87 0.97 (0.91–0.99) −20.0 (−27.4, −13.1) to 12.9 (5.8, 20.1) 4.1
 30-min post manganese T1 (ms) infarct 1137 ± 79 [996–1280] 1133 ± 80 [1009–1284] −4.2 0.87 0.97 (0.91–0.99) − 18.4 (−24.8, −12.7) to 8.9 (2.86, 14.82) 6.9
 Manganese uptake (Ki, mL/100 g of tissue/min) infarct 5.3 ± 1.4 [2.0–7.3] 5.4 ± 1.4 [3.0–7.4]  + 0.06 0.95 0.98 (0.94–0.99) − 0.4 (−0.8, −0.3) to 0.6 (0.3, 0.7) 8.1
Hypertrophic cardiomyopathy (n = 18)
 Native T1 (ms) non fibrosis 1185 ± 35 [1104–1237] 1188 ± 33 [1112–1240]  + 2.9 0.96 0.98 (0.93–0.99) − 15.1 (−20.7, −9.5) to 9.2 (3.6, 14.7) 2.9
 30-min post manganese T1 (ms) non fibrosis 922 ± 44 [838–994] 919 ± 40 [848–980] −3.0 0.80 0.95 (0.81–0.98) − 11.2 (−17.4, −4.8) to 15.1 (8.83, 21.4) 4.1
 Manganese uptake (Ki, mL/100 g of tissue/min) 7.6 ± 1.6 [4.0–9.9] 7.7 ± 0.7 [7.4–9.4]  + 0.07 0.96 0.97 (0.93–0.99) − 0.6 (−0.8, −0.1) to 0.4 (0.2, 0.7) 7.4
Dilated cardiomyopathy (n = 10)
 Native T1 (ms) 1208 ± 6 [1164–1252] 1206 ± 61 [1162–1250] −2.7 0.92 0.99 (0.97–1.0) −15.6 (−25.6, −6.1) to 11.4 (1.78, 20.9) 5.9
 30-min post manganese T1 (ms) 981 ± 58 [923–1039] 985 ± 61 [924–1046]  + 5.1 0.85 0.97 (0.83–0.97) −22.5 (−25.5, −13.2) 18.4 (1.1, 24.5) 6.3
 Manganese uptake (Ki, mL/100 g of tissue/min) non fibrosis 7.2 ± 1.5 [6.2–8.3] 7.4 ± 1.3 [6.4–8.3]  + 0.2 0.81 0.95 (0.84–0.98) − 0.9 (−1.5, −0.4) to 0.6 (0.04, 1.16) 12.5

Mean ± standard deviation [95% confidence interval].

LCC Lin’s concordance correlation, LoA limits of agreement, CoV coefficient of variation.