Table 2.
Intra-observer repeatability for patients with myocardial infarction (infarct), hypertrophic cardiomyopathy (non-fibrosis) or dilated cardiomyopathy.
Myocardial infarction (n = 20) | First measurement | Second measurement | Mean difference | P value | LCC (95% CI) | Bland–Altman (95% LoA) | CoV (%) |
---|---|---|---|---|---|---|---|
Native T1 (ms) infarct | 1395 ± 72 [1246–1501] | 1391 ± 74 [1241–1485] | −3.8 | 0.87 | 0.97 (0.91–0.99) | −20.0 (−27.4, −13.1) to 12.9 (5.8, 20.1) | 4.1 |
30-min post manganese T1 (ms) infarct | 1137 ± 79 [996–1280] | 1133 ± 80 [1009–1284] | −4.2 | 0.87 | 0.97 (0.91–0.99) | − 18.4 (−24.8, −12.7) to 8.9 (2.86, 14.82) | 6.9 |
Manganese uptake (Ki, mL/100 g of tissue/min) infarct | 5.3 ± 1.4 [2.0–7.3] | 5.4 ± 1.4 [3.0–7.4] | + 0.06 | 0.95 | 0.98 (0.94–0.99) | − 0.4 (−0.8, −0.3) to 0.6 (0.3, 0.7) | 8.1 |
Hypertrophic cardiomyopathy (n = 18) | |||||||
---|---|---|---|---|---|---|---|
Native T1 (ms) non fibrosis | 1185 ± 35 [1104–1237] | 1188 ± 33 [1112–1240] | + 2.9 | 0.96 | 0.98 (0.93–0.99) | − 15.1 (−20.7, −9.5) to 9.2 (3.6, 14.7) | 2.9 |
30-min post manganese T1 (ms) non fibrosis | 922 ± 44 [838–994] | 919 ± 40 [848–980] | −3.0 | 0.80 | 0.95 (0.81–0.98) | − 11.2 (−17.4, −4.8) to 15.1 (8.83, 21.4) | 4.1 |
Manganese uptake (Ki, mL/100 g of tissue/min) | 7.6 ± 1.6 [4.0–9.9] | 7.7 ± 0.7 [7.4–9.4] | + 0.07 | 0.96 | 0.97 (0.93–0.99) | − 0.6 (−0.8, −0.1) to 0.4 (0.2, 0.7) | 7.4 |
Dilated cardiomyopathy (n = 10) | |||||||
---|---|---|---|---|---|---|---|
Native T1 (ms) | 1208 ± 6 [1164–1252] | 1206 ± 61 [1162–1250] | −2.7 | 0.92 | 0.99 (0.97–1.0) | −15.6 (−25.6, −6.1) to 11.4 (1.78, 20.9) | 5.9 |
30-min post manganese T1 (ms) | 981 ± 58 [923–1039] | 985 ± 61 [924–1046] | + 5.1 | 0.85 | 0.97 (0.83–0.97) | −22.5 (−25.5, −13.2) 18.4 (1.1, 24.5) | 6.3 |
Manganese uptake (Ki, mL/100 g of tissue/min) non fibrosis | 7.2 ± 1.5 [6.2–8.3] | 7.4 ± 1.3 [6.4–8.3] | + 0.2 | 0.81 | 0.95 (0.84–0.98) | − 0.9 (−1.5, −0.4) to 0.6 (0.04, 1.16) | 12.5 |
Mean ± standard deviation [95% confidence interval].
LCC Lin’s concordance correlation, LoA limits of agreement, CoV coefficient of variation.