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. 2023 Feb 27;13:3366. doi: 10.1038/s41598-023-29591-z

Table 3.

Inter-observer repeatability for patients with myocardial infarction (infarct), hypertrophic cardiomyopathy (non-fibrosis) or dilated cardiomyopathy.

Myocardial infarction (n = 20) First observer Second observer Mean Difference P value LCC (95% CI) Bland–Altman (95% LoA) CoV (%)
 Native T1 (ms) infarct 1395 ± 72 [1246–1501] 1390 ± 74 [1222–1484] −4.4 0.83 0.98 (0.70–0.97) −21.4 (−32.2, −10.5) to 28.9 (18.1, 39.80) 5.2
 30-min post manganese T1 (ms) infarct 1137 ± 79 [996–1280] 1141 ± 74 [1001–1271]  + 3.3 0.88 0.99 (0.97–0.99) −23.5 (−32.5, −14.7) to 17.6 (8.7, 26.5) 6.9
 Manganese uptake (Ki, mL/100 g of tissue/min) infarct 5.3 ± 1.4 [2.0–7.3] 5.2 ± 1.3 [2.9–7.3] −0.08 0.79 0.98 (0.96–0.99) − 0.7 (−1.03, −0.4) to 0.9 (0.5, 1.2) 9.9
Hypertrophic cardiomyopathy (n = 18)
 Native T1 (ms) non fibrosis 1185 ± 35 [1104–1237] 1189 ± 33 [110–1206]  + 3.9 0.88 0.97 (0.84–0.98) −26.8 (−37.6, −16.2) to 19.1 (8.5, 27.7) 3.1
 30-min post manganese T1 (ms) non fibrosis 922 ± 44 [838–994] 917 ± 45 [844–975] −4.8 0.82 0.97 (0.94–0.99) − 11.6 (−19.8, −3.4) to 22.7 (914.5, 31.0) 4.3
 Manganese uptake (Ki, mL/100 g of tissue/min) non fibrosis 7.6 ± 1.6 [4.0–9.9] 7.4 ± 1.6 [3.09–9.8] −0.2 0.89 0.98 (0.96–0.99) − 0.3 (−0.6, −1.0) to 0.7 (0.5, 0.9) 8.2
Dilated cardiomyopathy (n = 10)
 Native T1 (ms) 1208 ± 60 [1164–1252] 1206 ± 68 [1157–1256] −2.2 0.94 0.98 (0.94–0.99) −17.7 (−31.2, −4.1) to 20.3 (6.7, 33.20) 5.8
 30-min post manganese T1 (ms) 981 ± 58 [923–1039] 977 ± 57 [920–1034] −4.6 0.88 0.98 (0.69–0.92) − 20.6 (−32.3, −8.9) to 12.4 (90.65, 24.1) 6.5
 Manganese uptake (Ki, mL/100 g of tissue/min) 7.2 ± 1.5 [6.2–8.3] 7.1 ± 1.3 [6.2–8.0] −0.1 0.90 0.95 (0.79–0.99) −0.8 (−1.1, −0.2) to 0.9 (0.2, 1.1) 13.2

Mean ± standard deviation [95% confidence interval].

LCC Lin’s concordance correlation, LoA limits of agreement, CoV coefficient of variation.