Table 1. Demographic, Clinical, and Biochemical Characteristics of the Study Participants at Baseline.
Parameters | Atorvastatin (20 mg) (n=44) | Rosuvastatin (10 mg) (n=45) | Pitavastatin (2 mg) (n=42) | p value | |
---|---|---|---|---|---|
Male | 20 (45.4) | 13 (28.8) | 14 (33.3) | 0.24 | |
Age, yr | 58.8±9.7 | 58.7±12.0 | 57.9±9.4 | 0.91 | |
Hypertension | 15 (34.1) | 17 (37.8) | 11 (26.2) | 0.50 | |
Antidiabetic drugs | 35 (79.5) | 32 (71.1) | 33 (75.6) | ||
Metformin | 8 (22.9) | 10 (31.3) | 9 (27.3) | 0.88 | |
Metformin combinations* | 23 (65.7) | 20 (62.5) | 21 (63.6) | 0.75 | |
Others† | 4 (11.4) | 2 (6.2) | 3 (9.1) | 0.68 | |
FPG, mg/dL | 134.0 (122.5–149.7) | 134.0 (121.0–147.0) | 139.0 (112.0–185.3) | 0.59 | |
HbA1c, % | 6.0 (6.5–7.8) | 6.1 (6.8–8.2) | 7.5 (6.4–9.4) | 0.12 | |
Total cholesterol, mg/dL | 255.9±42.2 | 256.6±47.8 | 259.1±39.8 | 0.99 | |
LDL-C, mg/dL | 173.8±35 | 174.5±39.4 | 176.1±33 | 0.98 | |
HDL-C, mg/dL | 47.2±10.2 | 48.9±9.1 | 49±8.7 | 0.60 | |
Triglycerides, mg/dL | 177.5±64.4 | 172.6±68.2 | 179.5±66.9 | 0.88 |
FPG, fasting plasma glucose; HbA1c, Hemoglobin A1c; LDL-C, low-density lipoprotein-cholesterol; HDL-C, high-density lipoprotein-cholesterol.
Data are presented as means±SD, medians (Q1–Q3), or n (%). P-values refers to comparisons among drugs.
*Metformin+ GLP-1 RA or DPP4 or SGLT-2 inhibitors; †Insulin+ metformin or DPP4 inhibitors.